Aims: To quantify the prevalence of heart failure and left ventricular systolic dysfunction (LVSD)
in chronic obstructive pulmonary disease (COPD) patients and vice versa. Further, to …

Background Persons with Chronic Obstructive Pulmonary Disease (COPD), performing
some level of regular physical activity, have a lower risk of both COPD-related hospital …

Chronic obstructive pulmonary disease (COPD) is characterised by a chronic inflammation
in the pulmonary tissue. The disease is associated with a switch from a selflimiting …

Background There are limited data from randomized trials regarding whether volume-based,
low-dose computed tomographic (CT) screening can reduce lung-cancer mortality among …

Cell death is regulated mainly through an evolutionarily conserved form of cell suicide termed
apoptosis [1]. Deregulation of apoptosis has been associated with cancer, autoimmune …

Background The use of multidetector computed tomography (CT) in lung-cancer screening
trials involving subjects with an increased risk of lung cancer has highlighted the problem for …

Interleukin-3 (IL-3), IL-5, and granulocyte-macrophage colony-stimulating factor regulate the
survival, proliferation, and differentiation of hematopoietic lineages. Phosphatidylinositol 3-…

Aims To establish the prevalence of unrecognized heart failure in elderly patients with a
diagnosis of chronic obstructive pulmonary disease, in a stable phase of their disease. Methods …

Background The main challenge in CT screening for lung cancer is the high prevalence of
pulmonary nodules and the relatively low incidence of lung cancer. Management protocols …

The 89-kDa STAT3 protein is a latent transcription factor which is activated in response to
cytokines (interleukin (IL)-5 and −6) and growth factors (epidermal growth factor). Binding of IL-…