Deriving quality criteria for water and sediment from the results of aquatic toxicity tests and product standards: application of the equilibrium partitioning method

LA Van der Kooij, D Van De Meent, CJ Van Leeuwen… - Water Research, 1991 - Elsevier
The present paper summarizes an approach recently proposed in The Netherlands to use
the equilibrium partitioning (EP) method to derive a coherent set of quality criteria for aquatic …

Intelligent testing strategies

CJ Van Leeuwen, GY Patlewicz, AP Worth - Risk assessment of chemicals …, 2007 - Springer
In the context of regulatory programs for the safety evaluation of chemicals, there is a need
for a paradigm shift. The challenge is to move in a scientifically credible and transparent …

Ecotoxicological effects

TP Traas, CJV Leeuwen - Risk assessment of chemicals: an introduction, 2007 - Springer
Ecotoxicology is the study of toxic effects of substances on species in ecosystems and
involves knowledge of three main disciplines: toxicology, ecology and chemistry (Figure 7.1). …

Application of QSARs in risk management of existing chemicals

HJM Verhaar, CJ Van Leeuwen, J Bol… - SAR and QSAR in …, 1994 - Taylor & Francis
QSAR-estimates of aquatic toxicity of relatively unreactive (narcosis-type) organic chemicals
for 19 species were used to predict “no-effect-levels” (NELs) at the ecosystem level by …

Quality criteria and risk assessment for mixtures of chemicals in the aquatic environment

CJ Van Leeuwen, HJM Verhaar… - Human and Ecological …, 1996 - Taylor & Francis
Much of the information available on the ecotoxicity of substances relates to single chemicals
tested under laboratory conditions. Yet, it is strange to find an aquatic ecosystem which is …

[PDF][PDF] Effecten van microverontreinigingen op de populatiedynamica van Daphnia magna

CJ van Leeuwen, G Niebeek, W Luttmer - H2O, 1987 - edepot.wur.nl
Het vaststellen van relevante en hanteerbare toxiciteitscriteria wordt steeds belangrijker,
mede gezien de grote aantallen microverontreinigingen die potentieel schadelijk kunnen zijn …

[PDF][PDF] Hoe giftig is regenwater?

J De Poorte, CJ Van Leeuwen - H2O, 1997 - edepot.wur.nl
Hoe giftig is regenwater? In dit artikel wordt een ecotoxicologische risicoschatting gemaakt
voor enkele gehalten aan bestrijdingsmiddelen in regenwater, verzameld op 4 locaties in …

Emissions of Chemicals to The Environment

PVD Poel, DN Brooke, CJV Leeuwen - Risk Assessment of Chemicals: An …, 2007 - Springer
2. EMISSIONS OF CHEMICALS TO THE ENVIRONMENT Page 1 2.1 INTRODUCTION The
essence of risk assessment of chemicals (Chapter 1) is the comparison of exposure (the …

The management of industrial chemicals in the EU

CJV Leeuwen, BG Hansen, JHMD Bruijn - Risk Assessment of Chemicals …, 2007 - Springer
Chemicals are used to make virtually every man-made product and play an important role in
the everyday life of people around the world. The chemical industry is the third largest …

[PDF][PDF] 11. Intelligent testing strategies

CJ van Leeuwen, GY Patlewicz, AP Worth - medicine, 2007 - researchgate.net
In the context of regulatory programs for the safety evaluation of chemicals, there is a need
for a paradigm shift. The challenge is to move in a scientifically credible and transparent …