Determination of the oxidation state of Tc in 99Tc (Sn) EHDP, 99mTc (Sn) EHDP, 99Tc (Sn) MDP and 99mTc (Sn) MDP complexes. Characterization of Tc (III)-, Tc (IV) …

TG Tji, HA Vink, WJ Gelsema, CL De Ligny - International Journal of …, 1990 - Elsevier
The oxidation state of complexed Tc was determined, by performing paper and thin-layer
chromatography during potentiometric titrations. Both titrations of Sn(II) with TcO 4 − and of TcO …

The valence state of technetium-99 in its complexes with bleomycin, 1-hydroxy-ethylidene-1, 1-diphosphonate and human serum albumin

J Korteland, BG Dekker, CL De Ligny - The International Journal of Applied …, 1980 - Elsevier
The valence state of technetium-99 in its complexes with bleomycin, 1-hydroxy-ethylidene-1,1-diphosphonate
and human serum albumin was determined by titration of 99 TcO 4 − with …

Sup (99m) Tc bone scanning agents: Pt. 6. Gel chromatographic analysis of the plasma protein binding of/sup 99m/Tc (Sn) pyrophosphate,/sup 99m/Tc (Sn) MDP and …

J Kroesbergen, AMP Roozen, MR Wortelboer… - Nucl. Med. Biol.;(United …, 1988 - osti.gov
The plasma binding of Tc-complexes of pyrophosphate, MDP and HMDP was investigated
in vitro using gel chromatography on Biogel P-200. Binding percentages ranging from 5-15% …

System for high performance liquid chromatography of sup (99m) Tc-compounds with on-line radiometric detection and data processing

GJ De Groot, HA Das, CL De Ligny - Int. J. Appl. Radiat. Isot.;(United …, 1985 - osti.gov
A system for HPLC with on-line ..gamma.. activity (two channels) and uv-detection is
described, including software for the on-line data processing with a microcomputer. It was …

The influence of Sn (IV) on the mean size of 99mTc (Sn) MDP constituents at neutral pH

WJ Gelsema, CL De Ligny, TG Tji - … . Part A. Applied Radiation and Isotopes, 1987 - Elsevier
The effect of addition of Sn (IV), Mg (II) and Ca (II) on the mean size of the 99m Tc-containing
constituents of a 99m Tc (Sn) MDP reaction mixture was determined by a gel …

A chromatographic study of the composition of [99mTc] Tc (Sn) EHDP complexes

CL De Ligny, WJ Gelsema, WE Meijs - International journal of radiation …, 1991 - Elsevier
Tc(Sn)EHDP complexes were prepared under different reaction conditions, and the composition
of the reaction mixture was investigated by anion exchange HPLC on Aminex A 28. The …

Separation of 99mTc(Sn)-EHDP complexes by chromatography on TSK G 2000 PW, using its ion exchange properties

YM Huigen, WJ Gelsema, CL De Ligny - Applied Radiation and …, 1990 - inis.iaea.org
[en] Skeletal imaging agents, labelled with 99m Tc are widely used in nuclear medicine.
Preparation of these agents yields a mixture of complexes that show different biodistributions (…

Binding of sup 99m Tc (Sn)-MDP complexes to human serum albumin and other blood proteins determined with gel chromatography and ultrafiltration

YM Huigen, TG Tji, WJ Gelsema, CL de Ligny - Applied Radiation and …, 1989 - osti.gov
The binding of {sup 99m}Tc(Sn)-MDP to human serum albumin and other blood proteins
was investigated by gel chromatography and ultrafiltration. During gel chromatography …

Investigation of two new [[sup 99m] Tc] Tc-HEDP preparations that can be expected to give a better lesion-to-normal-bone uptake ratio when used as bone scanning …

CL de Ligny, WJ Gelsema, TPM Hoevelaken… - Nuclear Medicine and …, 1993 - osti.gov
Two new potential bone scanning agents have been prepared and characterized. One of
the agents Tc(Sn,pH 12)-HEDP, is prepared at pH 12 (and subsequently neutralized). The …

Determination of the oxidation state of Tc in sup 99 Tc (Sn) EHDP, sup 99m Tc (Sn) EHDP, sup 99 Tc (Sn) MDP and sup 99m Tc (Sn) MDP complexes …

TG Tji, HA Vink, WJ Gelsema, CL de Ligny - Applied Radiation and …, 1990 - osti.gov
The oxidation state of complexed Tc was determined, by performing paper and thin-layer
chromatography during potentiometric titrations. Both titrations of Sn(II) with TcO{sub 4}{sup -} …