Despite their enormous diversity in biological function and structure, peptides and proteins
are endowed with properties that have induced and stimulated the development of …

In this review, the synthesis and application of biomedical and pharmaceutical polymers
synthesized via the copper(I)-catalyzed alkyne-azide cycloaddition, the thiol−ene reaction, or a …

Nanomedicines are used to improve the efficacy and safety of pharmacotherapeutic
interventions. Unraveling the biological behavior of nanomedicines, including their biodistribution …

Specific interactions of membrane proteins with the membrane interfacial region potentially
define protein position with respect to the lipid environment. We investigated the proposed …

Purpose The integrin α v β 3 is expressed on sprouting endothelial cells and on various
tumour cell types. Due to the restricted expression of α v β 3 in tumours, α v β 3 is considered a …

Galectins are mammalian carbohydrate‐binding proteins that are involved in cell–cell and
cell–matrix adhesion, cell migration, and growth regulation with relevance to inflammation …

This report describes the design and synthesis of a series of αVβ3 integrin-directed monomeric,
dimeric and tetrameric cyclo[Arg-Gly-Asp-D-Phe-Lys] dendrimers using “click chemistry”. …

Amyloid deposits in the pancreatic islets of Langerhans are thought to be a main factor
responsible for death of the insulin-producing islet β-cells in type 2 diabetes. It is hypothesized …

Solid-state NMR methods employing 2 H NMR and geometric analysis of labeled alanines (GALA)
were used to study the structure and orientation of the transmembrane α-helical …

Herein we describe the synthesis and rheological characterization of a series of
enzymatically sensitive PEG and peptide-based hydrogels by the Cu(I)-catalyzed 1,3-dipolar …