Accurate quantification of in vivo 31P NMR signals using the variable projection method and prior knowledge

JWC Van der Veen, R De Beer… - Magnetic …, 1988 - Wiley Online Library
Free induction decay signals are analyzed by fitting a model function directly in the time
domain. No starting values are needed for linear model parameters, and omission of corrupted …

Metabolic imaging of patients with intracranial tumors: H-1 MR spectroscopic imaging and PET.

PR Luyten, AJ Marien, W Heindel, PH Van Gerwen… - Radiology, 1990 - pubs.rsna.org
Hydrogen-1 magnetic resonance (MR) spectroscopic images of patients with intracranial
tumors were obtained. Metabolite maps of N-acetyl aspartate, choline, lactate, and creatine …

Inflow versus deoxyhemoglobin effects in BOLD functional MRI using gradient echoes at 1.5 T

JH Duyn, CTW Moonen, GH van Yperen… - NMR in …, 1994 - Wiley Online Library
Modified gradient‐echo MR techniques were applied to study the effects of inflow on functional
brain imaging studies using visual and motor cortex stimulation. The results demonstrate …

Detection of metabolic heterogeneity of human intracranial tumors in vivo by 1h nmr spectroscopic imaging

CM Segebarth, DF Balériaux, PR Luyten… - Magnetic resonance …, 1990 - Wiley Online Library
Patients with intracranial tumors (gliomas) were examined by means of localized water‐suppressed
1 H NMR single volume spectroscopy and spectroscopic imaging. The 1 H NMR …

Broadband proton decoupling in human 31p NMR spectroscopy

PR Luyten, G Bruntink, FM Sloff… - NMR in …, 1989 - Wiley Online Library
The limited chemical shift dispersion of in vivo 31 P NMR spectra obtained at the relatively
low field strengths used for human applications is the cause of poor spectral resolution. This …

Human breast cancer in vivo: H-1 and P-31 MR spectroscopy at 1.5 T.

PE Sijens, HK Wijrdeman, MA Moerland, CJ Bakker… - Radiology, 1988 - pubs.rsna.org
To assess the potential of in vivo magnetic resonance (MR) spectroscopy for breast cancer,
hydrogen-1 and phosphorus-31 MR spectra of five malignant human breast tumors were …

Cardiac metabolism in patients with dilated and hypertrophic cardio‐myopathy: Assessment with proton‐decoupled P‐31 MR spectroscopy

A De Roos, J Doornbos, PR Luyten… - Journal of Magnetic …, 1992 - Wiley Online Library
Proton‐decoupled phosphorus‐31 heart spectros‐copy was performed in healthy subjects (n
= 9) and patients with dilated cardiomyopathy (DCM, n = 9) or hypertrophic …

Acquisition and quantitation in proton spectroscopy

PR Luyten, AJH Mariën… - NMR in Biomedicine, 1991 - Wiley Online Library
Localized proton NMR spectroscopy in the human brain is one of the more technically
advanced applications of human in vivo NMR spectroscopy. Spin/echo techniques introduced …

In vivo imaging of glucose consumption and lactate concentration in human gliomas

K Herholz, W Heindel, PR Luyten… - Annals of Neurology …, 1992 - Wiley Online Library
Twenty patients with histologically confirmed gliomas were studied with positron emission
tomography (PET) and proton magnetic resonance spectroscopy ( 1 H‐MRS). PET with 18 F‐2…

Observation of metabolites in the human brain by MR spectroscopy.

PR Luyten, JA den Hollander - Radiology, 1986 - pubs.rsna.org
Measurement of low molecular weight metabolites by hydrogen magnetic resonance (MR)
spectroscopy is complicated by the presence of intense signals from water and lipids. A …