A meta-analysis of outcomes of conventional IVF in women with polycystic ovary syndrome

E Heijnen, MJC Eijkemans, EG Hughes… - Human reproduction …, 2006 - academic.oup.com
This meta-analysis was conducted to compare outcomes of conventional IVF in women
presenting with polycystic ovary syndrome (PCOS) and non-PCOS patients. Studies in which …

A meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome

CM Boomsma, MJC Eijkemans… - Human reproduction …, 2006 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a common reproductive disorder associated with
many characteristic features, including hyperandrogenaemia, insulin resistance and obesity …

Conception to ongoing pregnancy: the 'black box'of early pregnancy loss

NS Macklon, JPM Geraedts… - Human reproduction …, 2002 - academic.oup.com
Even when conditions are optimal, the maximum chance of a clinically recognized pregnancy
occurring in a given menstrual cycle is 30–40%. Increasing evidence points to preclinical …

The Science behind 25 Years of Ovarian Stimulation for in Vitro Fertilization

NS Macklon, RL Stouffer, LC Giudice… - Endocrine …, 2006 - academic.oup.com
To allow selection of embryos for transfer after in vitro fertilization, ovarian stimulation is
usually carried out with exogenous gonadotropins. To compensate for changes induced by …

Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: a randomized controlled trial

EB Baart, E Martini, MJ Eijkemans… - Human …, 2007 - academic.oup.com
BACKGROUND To test whether ovarian stimulation for in-vitro fertilization (IVF) affects oocyte
quality and thus chromosome segregation behaviour during meiosis and early embryo …

Multiple birth resulting from ovarian stimulation for subfertility treatment

BCJM Fauser, P Devroey, NS Macklon - The Lancet, 2005 - thelancet.com
Assisted reproductive technologies (ARTs) aim to increase a woman's chances of becoming
pregnant by bringing many female and male gametes into close proximity. Techniques to …

Anti-Müllerian hormone (AMH): what do we still need to know?

A La Marca, FJ Broekmans, A Volpe… - Human …, 2009 - academic.oup.com
In the ovary, Anti-Müllerian hormone (AMH) is produced by the granulosa cells of early
developing follicles and inhibits the transition from the primordial to the primary follicular stage. …

Embryonic implantation: cytokines, adhesion molecules, and immune cells in establishing an implantation environment

MSM Van Mourik, NS Macklon… - Journal of Leucocyte …, 2009 - academic.oup.com
Successful implantation is an absolute requirement for the reproduction of species,
including humans. The process by which a foreign blastocyst is accepted by the maternal …

Female reproductive ageing: current knowledge and future trends

FJ Broekmans, EAH Knauff, ER te Velde… - Trends in Endocrinology …, 2007 - cell.com
Over the past few decades, postponement of childbearing has led to a decrease in family
size and increased rates of age-related female subfertility. Age-related decrease in ovarian …

Natural selection of human embryos: impaired decidualization of endometrium disables embryo-maternal interactions and causes recurrent pregnancy loss

M Salker, G Teklenburg, M Molokhia, S Lavery, G Trew… - PloS one, 2010 - journals.plos.org
Background Recurrent pregnancy loss (RPL), defined as 3 or more consecutive miscarriages,
is widely attributed either to repeated chromosomal instability in the conceptus or to …