1-Aryl-piperazine compounds are, depending on their substituents, selective for certain
serotonin receptors and together with their easy availability and their so-called legal status, this …

Since the introduction of radioiodinated metaiodobenzylguanidine in 1980, considerable
research has been performed, both in the chemical field and in medical sciences. However, …

Recent years have seen the development of powerful technologies that have provided forensic
scientists with new analytical capabilities, unimaginable only a few years ago. With liquid …

The objective of this study was to investigate the effects of methylphenidate (MPH) on
attention and inhibition in children with Attention Deficit Hyperactivity Disorder (ADHD) and to …

Background: Serotonin (5-HT) plays a complex regulatory role in processes like anxiety,
depression, aggression, and impulse control. Due to the large amount of serotonergic receptors, …

In drug analysis, research involving the use of saliva sampling as non-invasive qualitative
and quantitative techniques have become increasingly important. Being readily accessible …

5-HT 1B receptors have a regulatory role in serotonergic activity and influence feeding behavior
and body weight. Because the absence of 5-HT 1B receptors may cause changes in this …

To study the potential of hair as a biological specimen in therapeutic drug monitoring (TDM),
a review of the correlation between hair concentration, blood levels, dose and therapeutic …

Carboplatin is a chemotherapeutic agent frequently used in the treatment of various
malignancies. The myelotoxicity and clinical efficacy of carboplatin correlate with the clearance of …

Target analysis of amphetamines in biological samples is of great importance for clinical
and forensic toxicologists alike. At present, most laboratories analyze such samples by gas …