An overview of cancer pathogenesis, diagnosis, and management.

JM Cullen, R Page, W Misdorp - Tumors in domestic animals, 2002 - cabdirect.org
This chapter covers: the molecular basis of cancer including oncogenes, tumour suppressor
genes, and regulators of apoptosis, the growth of tumours including metastasis, aetiologies …

Mast cells and canine mast cell tumours. A review

W Misdorp - Veterinary quarterly, 2004 - Taylor & Francis
This article reviews the literature on mast cells and tumours derived from mast cells in the
dog. Mast cells play a central role in inflammatory and inunune reactions. Mast cells, normal …

Hormonal background of canine and feline mammary tumours.

GR Rutteman, W Misdorp - Journal of Reproduction and fertility …, 1993 - europepmc.org
Ovarian steroid hormones and their synthetic derivatives may enhance mammary tumorigenesis
in dogs and cats. In toxicity studies of synthetic progestagens a dose-related effect has …

Proposal of a 2-tier histologic grading system for canine cutaneous mast cell tumors to more accurately predict biological behavior

M Kiupel, JD Webster, KL Bailey, S Best… - Veterinary …, 2011 - journals.sagepub.com
Currently, prognostic and therapeutic determinations for canine cutaneous mast cell tumors (MCTs)
are primarily based on histologic grade. However, the use of different grading …

Tumours and dysplasias of the mammary gland

JF Hampe, W Misdorp - Bulletin of the World Health Organization, 1974 - ncbi.nlm.nih.gov
As mammary tumours occur frequently in the dog and cat but rarely in other domestic animals,
only the tumours of these two species are classified. The epithelial tumours are termed “…

Some prognostic and epidemiologic factors in canine osteosarcoma

W Misdorp, AAM Hart - Journal of the National Cancer Institute, 1979 - academic.oup.com
Naturally occurring skeletal osteosarcomas in a series of 144 untreated dogs were found
especially to involve the ends of the long bones of the forelimbs and affected predominantly …

Feline mammary tumors: a case-control study of hormonal factors.

W Misdorp, A Romijn, AA Hart - Anticancer research, 1991 - europepmc.org
Feline mammary carcinomas are, like human breast cancers, spontaneous, locally
infiltrative and metastasizing tumors. Therefore, this tumor disease in the cat can serve as a …

Prognostic factors in canine mammary cancer

W Misdorp, AAM Hart - Journal of the National Cancer Institute, 1976 - academic.oup.com
… (4) HAMPE JF, MISDORP W: Tumours and dysplasias of the mammary gland. Bull WHO 50:…
1963, p 991 (Ii) MISDORP W: Malignant mammary tumors in the dog and the cat compared …

Feline malignant mammary tumors. I. Morphology and biology: some comparisons with human and canine mammary carcinomas

K Weijer, KW Head, W Misdorp… - JNCI: Journal of the …, 1972 - academic.oup.com
The morphology and biology of 179 malignant mammary tumors from 170 cats were
described. The site of tumors was nearly equally distributed among the 4 pairs of glands. The …

Oestrogen (ER) and progestin receptors (PR) in mammary tissue of the female dog: different receptor profile in non-malignant and malignant states

GR Rutteman, W Misdorp, MA Blankenstein… - British journal of …, 1988 - nature.com
Oestrogen (ER) and progestin receptors (PR) were measured in cytosols from histologically
normal mammary tissues (n= 30), and in benign (n= 59) and malignant mammary lesions (n…