Regulatory toxicology urgently needs applicable alternative test systems that reduce animal
use, testing time, and cost. European regulation on cosmetic ingredients has already …

This paper surveys the scientific basis for the current threshold approach for reproductive
hazard and risk assessment. In some regulatory areas it was recently suggested to consider …

Because of the relatively high human oral exposure to polycyclic aromatic hydrocarbons (PAHs)
compared to the inhalation exposure, the known carcinogenicity of this type of …

Humans are exposed via the environment and via food to Polycyclic Aromatic Hydrocarbons
(PAH), mixtures considered carcinogenic by IARC. A quantitative cancer risk assessment …

To explain reciprocity, direct or indirect, several proximate mechanisms have been proposed,
yet little attention has been given to the specific underlying cognitive mechanisms. …

Structure-Activity Relationships (SARs), including Quantitative SARs, are applied to the hazard
assessment of chemicals. This need is all the more urgent considering the proposed new …

Research into the toxic effects of substances on humans can be traced back to the ancient
centres of civilization in Egypt, Greece and China, where toxic chemical substances were …

In this report an overview is given of structure-activity relationships (SARs) described in
literature that can be helpful for the daily human hazard evaluation of chemicals. SARs describe …

De GenX-technologie wordt gebruikt om onder andere coatings te produceren, zoals Teflon.
Hierbij komt de stof HFPO-DA (2,3,3,3-tetrafluor-2-(heptafluoropropoxy) propaanzuur, of …

Berichtgeving over de chemiefabriek Dupont/Chemours in Dordrecht heeft naar voren
gebracht dat werknemers in het verleden mogelijk zijn blootgesteld aan de stoffen PFOA (…