Hardeveld F, Spijker J, De Graaf R, Nolen WA, Beekman ATF. Prevalence and predictors of
recurrence of major depressive disorder in the adult population. Objective: Knowledge of the …

Objective The risk-benefit profile of antidepressant medications in bipolar disorder is
controversial. When conclusive evidence is lacking, expert consensus can guide treatment …

OBJECTIVE: This study reviewed the evidence from randomized, controlled trials on the
efficacy and safety of antidepressants in the short-term treatment of bipolar depression. …

… A, Beaulieu S, Alda M, O’Donovan C, MacQueen G, McIntyre RS, Sharma V, Ravindran A,
Young LT, Milev R, Bond DJ, Frey BN, Goldstein BI, Lafer B, Birmaher B, Ha K, Nolen WA, …

The Netherlands Study of Depression and Anxiety (NESDA) is a multi‐site naturalistic cohort
study to: (1) describe the long‐term course and consequences of depressive and anxiety …

Background: Comorbidity of depressive and anxiety disorders is common and has been shown
to be a consistent predictor of chronicity. Comorbidity patterns among specific depressive …

OBJECTIVE: Bipolar disorder often co-occurs with other axis I disorders, but little is known
about the relationships between the clinical features of bipolar illness and these comorbid …

BackgroundData on the duration of major depressive episodes (MDE) in the general
population are sparse.AimsTo assess the duration of MDE and its clinical and socio-demographic …

Background: Since recent NIMH Bipolar Disorder Workshops highlighted the dearth of
longitudinal and controlled studies of bipolar illness, the Stanley Foundation Bipolar Network (…

Objectives: Via an international panel of experts, this paper attempts to document, review,
interpret, and propose operational definitions used to describe the course of bipolar disorders …