Developmental neuroplasticity and the origin of neurodegenerative diseases

ATU Schaefers, G Teuchert-Noodt - The World Journal of Biological …, 2016 - Taylor & Francis
Objectives. Neurodegenerative diseases like Alzheimer's and Parkinson's Disease, marked
by characteristic protein aggregations, are more and more accepted to be synaptic disorders …

[HTML][HTML] Influence of methylphenidate on brain development–an update of recent animal experiments

T Grund, K Lehmann, N Bock, A Rothenberger… - Behavioral and Brain …, 2006 - Springer
Methylphenidate (MPH) is the most commonly used drug to treat attention deficit/hyperactivity
disorder (ADHD) in children effectively and safely. In spite of its widespread application …

Offer and demand: proliferation and survival of neurons in the dentate gyrus

K Lehmann, M Butz… - European Journal of …, 2005 - Wiley Online Library
The proliferation and survival of new cells in the dentate gyrus of mammals is a complex
process that is subject to numerous influences, presenting a confusing picture. We suggest …

Adult treatment with methamphetamine transiently decreases dentate granule cell proliferation in the gerbil hippocampus

G Teuchert-Noodt, RR Dawirs… - Journal of neural …, 2000 - Springer
The objective of the present study was to examine whether acute treatment with the recreational
drug methamphetamine influences adult granule cell proliferation in the dentate gyrus of …

Adult treatment with haloperidol increases dentate granule cell proliferation in the gerbil hippocampus

RR Dawirs, K Hildebrandt… - Journal of neural …, 1998 - Springer
Male gerbils were bred and reared grouped under enriched semi-natural environmental
conditions. The objective of the present study was to examine the influence of an acute …

Social environment alters both ontogeny of dopamine innervation of the medial prefrontal cortex and maturation of working memory in gerbils (Meriones unguiculatus …

KT Winterfeld, G Teuchert‐Noodt… - Journal of …, 1998 - Wiley Online Library
Male gerbils (Meriones unguiculatus) were bred and reared either grouped under enriched
environmental conditions or isolated under impoverished environmental conditions. The …

A theoretical network model to analyse neurogenesis and synaptogenesis in the dentate gyrus

M Butz, K Lehmann, IE Dammasch, G Teuchert-Noodt - Neural Networks, 2006 - Elsevier
We describe a strongly biologically motivated artificial neural network approach to model
neurogenesis and synaptic turnover as it naturally occurs for example in the hippocampal …

Inverse relationship between adult hippocampal cell proliferation and synaptic rewiring in the dentate gyrus

M Butz, G Teuchert‐Noodt, K Grafen… - …, 2008 - Wiley Online Library
… Butz M, Teuchert-Noodt G. 2006. A simulation model for compensatory plasticity in the
prefrontal cortex inducing a cortico-cortical dysconnection in early brain development. …

Differential environment alters ontogeny of dopamine innervation of the orbital prefrontal cortex in gerbils

J Neddens, K Brandenburg… - Journal of …, 2001 - Wiley Online Library
Numerous studies have shown that different rearing conditions may cause severe structural
and functional alterations in various regions of the brain. For example, restricted rearing can …

Serotonin fibre densities in subcortical areas: differential effects of isolated rearing and methamphetamine

K Lehmann, J Lesting, D Polascheck… - Developmental brain …, 2003 - Elsevier
Serotoninergic neurons interact with dopaminergic cells on all levels and are physiologically
affected by both isolated rearing (IR) and a single early methamphetamine (MA) injection. …