The pH dependence of the binding of warfarin to human serum albumin has been studies
by circular dichroism, fluorescence, and equilibrium dialysis. The pH dependences of the …

This review is intended to summarize the study of specific binding of low molecular weight
substances to macromolecular systems by the application of optical rotatory dispersion-…

Sulphaethidole has been previously shown to have two classes of binding site on bovine
serum albumin (BSA). Only the primary binding site is capable of inducing optical activity in the …

A statistically unbiased method of estimating ligand-macromolecule binding constants from
experimental data is given, assuming a non-cooperative binding process. The new method is…

The molar ellipticity of the warfarin-albumin complex at 310 nm increases with pH from 6 to 9.
This pH dependence runs parallel with that of the molar ellipticity of the albumin alone at …

The binding of the non-steroidal anti-inflammatory drug, tolmetin (1-methyl-5-p-toluoylpyrrole-2-acetic
acid) to human serum albumin (HSA) has been shown by circular dichroism, …

The degradation of aspartame was studied under a range of conditions (pH, 2.0–4.0; ionic
strength, 0.05–0.50 M; temperature, 4–50C). The loss of aspartame and formation of its …

A peritoneal dialysate containing beta-cyclodextrin has been shown to accelerate the removal
of intravenously administered phenobarbital in rats. It was found that high concentrations …

The binding constants for racemic, R and S naproxen and ibuprofen to human serum albumin
have been determined by a circular dichroic technique. The ibuprofens and naproxens …

4. Method Known amounts of tetracycline were added to the solutions containing 3 μg ml− 1
and 10 μg ml− 1 europium (III). Ten microliters of 27.3 mg ml− 1 H 2 O 2 and 5 ml DABCO …