The nature of microglia fascinated many prominent researchers in the 19th and early 20th
centuries, and in a classic treatise in 1932, Pio del Rio-Hortega formulated a number of …

Tuberculosis of the central nervous system (CNS) is a highly devastating form of tuberculosis,
which, even in the setting of appropriate antitubercular therapy, leads to unacceptable …

Opioids (exogenous opiates and endogenous opioid peptides) have a diversity of effects on
the immune system. Although numerous studies have shown that opioid-induced …

Activated microglial have been proposed to play a pathogenetic role in immune-mediated
neurodegenerative diseases. To test this hypothesis, purified murine neonatal microglial were …

Objective. —To evaluate the efficacy and safety of anti—tumor necrosis factor α monoclonal
antibody (TNF-α MAb) in the treatment of patients with sepsis syndrome. Design. —…

The cytokines interleukin (IL)-1 and tumor necrosis factor (TNF)-α, produced by glial cells
within the brain, appear to contribute to the neuropathogenesis of several inflammatory …

… 9 Hickey WF: Leukocyte migration into the central nervous system; in Peterson PK,
Remington JS (eds): In Defense of the Brain: Current Concepts in the Immunopathogenesis and …

Apoptosis plays a critical role in normal brain development and in a number of neurodegenerative
diseases. Recently, opiates have been shown to promote apoptotic death of cells of …

To study the effect of wall protein A on bacterial opsonization, phagocytosis of 10 strains of
Staphylococcus aureus with high and low protein A contents was measured. Those strains …

Activated glial cells have been implicated in the neuropathogenesis of many infectious and
inflammatory diseases of the brain. A number of inflammatory mediators have been …