Asthma is a chronic disease characterized by airway inflammation, bronchial
hyperresponsiveness, and recurrent episodes of reversible airway obstruction. The disease is very …

Background Pharmacogenetics studies of anti‐inflammatory medication of asthma have
expanded rapidly in recent decades, but the clinical value of their findings remains limited. …

Asthma is one of the most common chronic diseases worldwide. There is a large inter‐individual
variability in response to asthma treatment. Most patients respond well to standard …

Interleukin-3 (IL-3), IL-5, and granulocyte-macrophage colony-stimulating factor regulate the
survival, proliferation, and differentiation of hematopoietic lineages. Phosphatidylinositol 3-…

The 89-kDa STAT3 protein is a latent transcription factor which is activated in response to
cytokines (interleukin (IL)-5 and −6) and growth factors (epidermal growth factor). Binding of IL-…

OBJECTIVE: Despite the importance of the chronic use of inhaled corticosteroids (ICS) in
maintaining asthma control, reported adherence varies between 40% and 60%. The Beliefs …

Signal transducers and activators of transcription (STATs) belong to a family of transcription
factors that were originally identified as mediators of cytokine-induced gene expression. …

Signal transducers and activators of transcription (STATs) are a family of transcription factors
that were originally identified as mediators of cytokine-induced gene expression. We and …

Cytokine receptors consist of multiple subunits, which are often shared between different
receptors, resulting in the functional redundancy sometimes observed between cytokines. The …

To cite this article: Koster ES, Maitland‐van der Zee A‐H, Tavendale R, Mukhopadhyay S,
Vijverberg SJH, Raaijmakers JAM, Palmer CNA. FCER2 T2206C variant associated with …