Immunomodulatory effects of macrolides during community-acquired pneumonia: a literature review

A Kovaleva, HHF Remmelts, GT Rijkers… - Journal of …, 2012 - academic.oup.com
Macrolides are known to possess immunomodulatory properties, next to their antimicrobial
effects. These immunomodulatory activities have been proven beneficial in chronic …

Dexamethasone and length of hospital stay in patients with community-acquired pneumonia: a randomised, double-blind, placebo-controlled trial

SCA Meijvis, H Hardeman, HHF Remmelts… - The Lancet, 2011 - thelancet.com
Background Whether addition of corticosteroids to antibiotic treatment benefits patients with
community-acquired pneumonia who are not in intensive care units is unclear. We aimed to …

Systemic and local medical or surgical therapies for ear, nose and/or throat manifestations in ANCA-associated vasculitis: a systematic literature review

RM Krol, HHF Remmelts, R Klaasen, A Frima… - Journal of Clinical …, 2023 - mdpi.com
Background: Ear, nose and throat (ENT) manifestations are common in patients with
antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), yet how to treat these …

Addition of vitamin D status to prognostic scores improves the prediction of outcome in community-acquired pneumonia

HHF Remmelts, EMW van de Garde… - Clinical infectious …, 2012 - academic.oup.com
Background. Vitamin D plays a role in host defense against infection. Vitamin D deficiency is
common worldwide. The prognostic value of vitamin D levels in pneumonia is unknown. In …

Dexamethasone downregulates the systemic cytokine response in patients with community-acquired pneumonia

HHF Remmelts, SCA Meijvis, DH Biesma… - Clinical and Vaccine …, 2012 - Am Soc Microbiol
The influence of adjunctive corticosteroids on the cytokine response in community-acquired
pneumonia (CAP) is largely unknown. In this study, we analyzed the effect of …

The prognostic value of amplitude integrated EEG in neonatal sepsis and/or meningitis

HJ Ter Horst, M Van Olffen, HJ Remmelts… - Acta …, 2010 - Wiley Online Library
Aim: To investigate the longitudinal course and prognostic value of amplitude integrated EEG
(aEEG) in infants with neonatal sepsis or meningitis. Methods: Amplitude integrated EEG …

[HTML][HTML] Compassionate Use of Avacopan in Difficult-to-Treat Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

JR van Leeuwen, OW Bredewold, LS van Dam… - Kidney international …, 2022 - Elsevier
Avacopan is a new, promising treatment for antineutrophil cytoplasmic antibody–associated
vasculitis (AAV) and can potentially, significantly reduce steroid use. There were 2 phase 2 …

Biomarkers define the clinical response to dexamethasone in community-acquired pneumonia

HHF Remmelts, SCA Meijvis, R Heijligenberg… - Journal of Infection, 2012 - Elsevier
OBJECTIVES: Adjuvant dexamethasone treatment in patients with community-acquired
pneumonia (CAP) can reduce length of hospital stay. Whether there are subgroups of patients …

The role of vitamin D supplementation in the risk of developing pneumonia: three independent case–control studies

HHF Remmelts, SMC Spoorenberg, JJ Oosterheert… - Thorax, 2013 - thorax.bmj.com
Background Vitamin D plays a role in host defence against infection. Vitamin D deficiency has
been associated with an increased risk of respiratory tract infections in children and adults…

ExploriNg DUrable Remission with Rituximab in ANCA-associatEd vasculitis (ENDURRANCE trial): protocol for a randomised controlled trial

E Dirikgil, JR van Leeuwen, LS van Dam… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Both rituximab (RTX) and cyclophosphamide (CYC) are effectively used in
combination with steroids as remission induction therapy for patients with antineutrophil …