Inhibition of d-amphetamine-induced locomotor activity by injection of haloperidol into the nucleus accumbens of the rat

AJJ Pijnenburg, WMM Honig, JM Van Rossum - Psychopharmacologia, 1975 - Springer
The effect of intracerebral administration of antagonists of dopamine and noradrenaline upon
the locomotor stimulation induced by intraperitoneal injection of d-amphetamine sulfate in …

Different types of sympathomimetic α‐receptors

JM Van Rossum - Journal of Pharmacy and Pharmacology, 1965 - Wiley Online Library
Sympathomimetic effects have been studied on the isolated vas deferens of the rat, in the
isolated jejunum of the rabbit and on the cardiovascular system of the cat. (–)‐Noradrenaline (1…

Ergometrine induced locomotor activity following intracerebral injection into the nucleus accumbens

AJJ Pijnenburg, GN Woodruff, JM Van Rossum - Brain research, 1973 - Elsevier
Ergometrine was injected in rats intraperitoneally or intravenously and also directly into
different parts of the brain. After peripheral injection the animals showed a characteristics …

Reversal of the effect of α‐methyldopa by monoamine oxidase inhibitors

JM Van Rossum… - Journal of Pharmacy and …, 1963 - Wiley Online Library
L‐α‐Methyldopa, which normally causes sedation, induces a strong central excitation in
mice pretreated with a monoamine oxidase inhibitor after a lag of a few hours. It is concluded …

Dose-dependent pharmacokinetics

JM Van Rossum, G Van Lingen, JPT Burgers - Pharmacology & …, 1983 - Elsevier
DOSE-DEPENDENT PHARMACOKINETICS JM VAN ROSSUM, G. VAN LINGEN and JPT
BURGERS 1. INTRODUCTION The profile of the concentr Page 1 Pharmac. Ther. Vol. 21, pp …

Bizarre social behaviour in rats induced by a combination of a peripheral decarboxylase inhibitor and DOPA

A Lammers, JM Van Rossum - European Journal of Pharmacology, 1968 - Elsevier
Male rats given a combination of the peripheral DOPA decarboxylase inhibitor Ro 4-4602
and DOPA, showed motor excitation as well as a peculiar and bizarre pattern of social …

Antagonism of apomorphine- and d-amphetamine-induced stereotyped behaviour by injection of low doses of haloperidol into the caudate nucleus and the nucleus …

AJJ Pijnenburg, WMM Honig, JM Van Rossum - Psychopharmacologia, 1975 - Springer
The effects of intracerebral injections of the dopa-mine-antagonist haloperidol upon stereotyped
behaviour, induced by peripheral administration of apomorphine and d-amphetamine in …

Systems dynamics in clinical pharmacokinetics: an introduction

JM Van Rossum, J De Bie - Clinical pharmacokinetics, 1989 - Springer
Pharmacokinetics is in essence the study of the input/output relationships of the (human)
body, which is considered as a system characterised by a density function of residence times. …

Effects of apomorphine on self-stimulation behavior

CLE Broekkamp, JM Van Rossum - Psychopharmacologia, 1974 - Springer
Self-stimulation behavior was studied in untreated rats and rats injected with apomorphine
with electrodes implanted in the nucleus accumbens, the lateral hypothalamus, the …

Absolute configuration and parasympathetic action: Pharmacodynamics of enantiomorphic and diastereoisomeric esters of β‐methylcholine

BWJ Ellenbroek, RJF Nivard… - Journal of Pharmacy …, 1965 - Wiley Online Library
The parasympathomimetic and atropine‐like actions of enantiomorphic esters of β‐methylcholine
and various esters of choline or β‐methylcholine containing an asymmetric centre in …