A liver biopsy is required to make the diagnosis of most non-vascular liver diseases. Liver
biopsy samples can be obtained with several techniques. With proper training and adequate …

Organoids derived from the liver have hepatocellular differentiation potential and can be an
unlimited source for hepatocytes for application in in vitro toxicology testing and for …

This paper presents a review of the literature on hepatic circulation and circulatory disorders
of the liver in the dog and cat, and also includes a number of our own not previously …

Domesticated animal species such as dogs and cats, with their many different characteristics
and breed-specific diseases, and their close relationship and shared environment with …

In determining relative gene expression by quantitative measurements of mRNA levels using
real-time quantitative PCR, internal standards such as reference genes are essential. Large…

Background: Little is known about etiology, disease progression, treatment outcome, survival
time, and factors affecting prognosis in dogs with primary hepatitis (PH). Objectives: To …

We have examined whether black/yellow coat colour in Labrador retrievers is controlled by
allelic variants at the extension locus. As the gene encoding the melanocyte‐stimulating …

This study summarizes the clinical and pathologic findings in 15 Labrador Retrievers with
copper‐associated chronic hepatitis (CACH). Our hypothesis was that this form of hepatitis is …

Hepatic steatosis is a highly prevalent liver disease, yet research is hampered by the lack of
tractable cellular and animal models. Steatosis also occurs in cats, where it can cause …

The recent development of 3D-liver stem cell cultures (hepatic organoids) opens up new
avenues for gene and/or stem cell therapy to treat liver disease. To test safety and efficacy, a …