Molecular interactions in the assembly of coronaviruses

CAM de Haan, PJM Rottier - Advances in virus research, 2005 - Elsevier
Publisher Summary This chapter describes the interactions between the different structural
components of the viruses and discusses their relevance for the process of virion formation. …

Virulence of Newcastle disease virus: what is known so far?

JCFM Dortmans, G Koch, PJM Rottier, BPH Peeters - Veterinary research, 2011 - Springer
In the last decade many studies have been performed on the virulence of Newcastle disease
virus (NDV). This is mainly due to the development of reverse genetics systems which …

[HTML][HTML] Cellular entry of the porcine epidemic diarrhea virus

W Li, FJM van Kuppeveld, Q He, PJM Rottier, BJ Bosch - Virus research, 2016 - Elsevier
Porcine epidemic diarrhea virus (PEDV), a coronavirus discovered more than 40 years ago,
regained notoriety recently by its devastating outbreaks in East Asia and the Americas, …

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

VS Raj, H Mou, SL Smits, DHW Dekkers, MA Müller… - Nature, 2013 - nature.com
Most human coronaviruses cause mild upper respiratory tract disease but may be associated
with more severe pulmonary disease in immunocompromised individuals 1 . However, …

The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex

BJ Bosch, R Van der Zee, CAM De Haan… - Journal of …, 2003 - Am Soc Microbiol
Coronavirus entry is mediated by the viral spike (S) glycoprotein. The 180-kDa oligomeric S
protein of the murine coronavirus mouse hepatitis virus strain A59 is posttranslationally …

Feline coronavirus type II strains 79-1683 and 79-1146 originate from a double recombination between feline coronavirus type I and canine coronavirus

AAPM Herrewegh, I Smeenk, MC Horzinek… - Journal of …, 1998 - Am Soc Microbiol
Recent evidence suggests that the type II feline coronavirus (FCoV) strains 79-1146 and 79-1683
have arisen from a homologous RNA recombination event between FCoV type I and …

Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

AC Walls, MA Tortorici, BJ Bosch, B Frenz, PJM Rottier… - Nature, 2016 - nature.com
The tremendous pandemic potential of coronaviruses was demonstrated twice in the past few
decades by two global outbreaks of deadly pneumonia. Entry of coronaviruses into cells is …

Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides

BJ Bosch, BEE Martina… - Proceedings of the …, 2004 - National Acad Sciences
The coronavirus SARS-CoV is the primary cause of the life-threatening severe acute
respiratory syndrome (SARS). With the aim of developing therapeutic agents, we have tested …

Retargeting of coronavirus by substitution of the spike glycoprotein ectodomain: crossing the host cell species barrier

L Kuo, GJ Godeke, MJB Raamsman… - Journal of …, 2000 - Am Soc Microbiol
Coronaviruses generally have a narrow host range, infecting one or just a few species. Using
targeted RNA recombination, we constructed a mutant of the coronavirus mouse hepatitis …

SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells

IC Huang, BJ Bosch, F Li, W Li, KH Lee… - Journal of Biological …, 2006 - ASBMB
Viruses require specific cellular receptors to infect their target cells. Angiotensin-converting
enzyme 2 (ACE2) is a cellular receptor for two divergent coronaviruses, SARS coronavirus (…