The outcome of recent studies has led to redefinition of concepts relating to the prevalence,
pathogenesis and clinical significance of disordered gastric emptying in patients with …

Acute changes in the blood glucose concentration have a major reversible effect on
esophageal, gastric, intestinal, gallbladder, and anorectal motility in both healthy subjects and …

Background Pragmatic randomised controlled trials are often used in primary care to evaluate
the effect of a treatment strategy. In these trials it is difficult to achieve both high internal …

Background & Aims: Esophageal acid exposure is higher in gastroesophageal reflux disease
(GERD) patients with hiatus hernia than in those without. We investigated the effect of a …

AIM: To determine the composition of both fecal and duodenal mucosa-associated
microbiota in irritable bowel syndrome (IBS) patients and healthy subjects using molecular-based …

Background & Aims: Although acid is likely to play a role in the genesis of symptoms in
dyspeptic patients, most studies have failed to show an increase in gastric acid secretion. The …

Background and aim: To detect precancerous dysplasia or asymptomatic cancer, patients
suffering from inflammatory bowel disease often undergo colonoscopic surveillance based on …

OBJECTIVES The roles of intragastric pressure (IGP), intraesophageal pressure (IEP),
gastroesophageal pressure gradient (GEPG), and body mass index (BMI) in the pathophysiology …

CXCR4 is the receptor for the CXC chemokine SDF1 that has essential functions on embryo
organogenesis, immunological functions and T lymphocyte trafficking. Recently, CXCR4 …

Background—Studies have shown that an altered visceral perception threshold plays a role
in the pathogenesis of upper gastrointestinal tract symptoms in dyspeptic patients. However, …