Extracellular matrix scaffolds for cartilage and bone regeneration
KEM Benders, PR Van Weeren, SF Badylak… - Trends in …, 2013 - cell.com
Regenerative medicine approaches based on decellularized extracellular matrix (ECM)
scaffolds and tissues are rapidly expanding. The rationale for using ECM as a natural …
scaffolds and tissues are rapidly expanding. The rationale for using ECM as a natural …
[HTML][HTML] Evaluation of histological scoring systems for tissue-engineered, repaired and osteoarthritic cartilage
M Rutgers, MJP Van Pelt, WJA Dhert… - Osteoarthritis and …, 2010 - Elsevier
OBJECTIVE: Regeneration of hyaline cartilage has been the focus of an increasing number
of research groups around the world. One of the most important outcome measures in …
of research groups around the world. One of the most important outcome measures in …
Treatment selection in articular cartilage lesions of the knee: a systematic review
JEJ Bekkers, M Inklaar… - The American journal of …, 2009 - journals.sagepub.com
Background Several treatment options are available to repair articular cartilage lesions of
the knee; however, evidence-based parameters for treatment selection are lacking. Purpose …
the knee; however, evidence-based parameters for treatment selection are lacking. Purpose …
Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial …
DBF Saris, J Vanlauwe, J Victor… - … American journal of …, 2009 - journals.sagepub.com
Background As the natural healing capacity of damaged articular cartilage is poor, joint
surface injuries are a prime target for regenerative medicine. Characterized chondrocyte …
surface injuries are a prime target for regenerative medicine. Characterized chondrocyte …
Treatment of symptomatic cartilage defects of the knee: characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial …
DBF Saris, J Vanlauwe, J Victor… - … American journal of …, 2009 - journals.sagepub.com
Background Damaged articular cartilage has limited capacity for self-repair. Autologous
chondrocyte implantation using a characterized cell therapy product results in significantly better …
chondrocyte implantation using a characterized cell therapy product results in significantly better …
[HTML][HTML] International Cartilage Repair Society (ICRS) and Oswestry macroscopic cartilage evaluation scores validated for use in Autologous Chondrocyte …
MPJ Van den Borne, NJH Raijmakers… - Osteoarthritis and …, 2007 - Elsevier
OBJECTIVE: For young patients with cartilage defects, the emergence of clinically applicable
cell therapy for biological joint reconstruction is an appealing prospect. Acceptation of this …
cell therapy for biological joint reconstruction is an appealing prospect. Acceptation of this …
Five-year outcome of characterized chondrocyte implantation versus microfracture for symptomatic cartilage defects of the knee: early treatment matters
J Vanlauwe, DBF Saris, J Victor… - … American journal of …, 2011 - journals.sagepub.com
Background: Characterized chondrocyte implantation (CCI) results in significantly better
early structural tissue regeneration than microfracture (MF), and CCI has a midterm clinical …
early structural tissue regeneration than microfracture (MF), and CCI has a midterm clinical …
Functional assessment and muscle strength before and after reconstruction of chronic anterior cruciate ligament lesions
SN de Jong, DR van Caspel, MJ van Haeff… - Arthroscopy: The Journal …, 2007 - Elsevier
Purpose: The goal of this study was to evaluate strength and functional capacity before and
after anterior cruciate ligament (ACL) reconstruction to determine the influences of …
after anterior cruciate ligament (ACL) reconstruction to determine the influences of …
[HTML][HTML] Validation of the Knee Injury and Osteoarthritis Outcome Score (KOOS) for the treatment of focal cartilage lesions
JEJ Bekkers, TS de Windt, NJH Raijmakers… - Osteoarthritis and …, 2009 - Elsevier
OBJECTIVE: To validate the Knee Injury and Osteoarthritis Outcome Score (KOOS) for the
treatment of focal cartilage lesions. METHODS: A total of 40 patients (mean age 35±12 years,) …
treatment of focal cartilage lesions. METHODS: A total of 40 patients (mean age 35±12 years,) …
[HTML][HTML] Mesenchymal stromal/stem cell-derived extracellular vesicles promote human cartilage regeneration in vitro
Osteoarthritis (OA) is a rheumatic disease leading to chronic pain and disability with no
effective treatment available. Recently, allogeneic human mesenchymal stromal/stem cells (MSC…
effective treatment available. Recently, allogeneic human mesenchymal stromal/stem cells (MSC…