G protein–coupled receptors trigger the reorganization of the actin cytoskeleton in many cell
types, but the steps in this signal transduction cascade are poorly understood. During …

During the early stages of its developmental program, Dictyostelium discoideum expresses
cell surface cyclic adenosine monophosphate (cyclic AMP) receptors. It has been suggested …

We are experiencing a revolution in cancer. Advances in screening, targeted and immune
therapies, big data, computational methodologies, and significant new knowledge of cancer …

Extracellular cAMP serves as a primary signaling molecule to regulate the development of
Dictyostelium discoideum. It is required for chemotaxis, aggregation, cytodifferentiation, and …

Two experiments were performed with five developmentally disabled individuals to test the
relationship between toys as conditioned reinforces and stereotypy. Data consisted of the …

We have previously reported the cloning of cDNAs for a Dictyostelium cell-surface cAMP
receptor that is a member of the family of G-protein-linked receptors. Here, we report the …

Scar, a member of the WASp protein family, was discovered in Dictyostelium discoideum
during a genetic screen for second-site mutations that suppressed a developmental defect. …

We have cloned and characterized three genes (CAR1, CAR2, CAR3) encoding potential
cell surface, cyclic adenosine 3′:5′ monophosphate (AMP) receptors from Dictyostelium …

Extracellular cAMP acts through cell-surface receptors to coordinate the developmental program
of Dictyostelium. A cAMP receptor (cAR1), which is expressed during early aggregation, …

cAMP receptors mediate signal transduction pathways during development in Dictyostelium.
A cAMP receptor (cAR1) has been cloned and sequenced (Klein, P., Sun, TJ, Saxe, CL, …