Microbial solubilization and immobilization of toxic metals: key biogeochemical processes for treatment of contamination

C White, JA Sayer, GM Gadd - FEMS microbiology reviews, 1997 - academic.oup.com
Microorganisms play important roles in the environmental fate of toxic metals with a
multiplicity of physico-chemical and biological mechanisms effecting transformations between …

[HTML][HTML] Forest Resources Assessment of 2015 shows positive global trends but forest loss and degradation persist in poor tropical countries

S Sloan, JA Sayer - Forest Ecology and Management, 2015 - Elsevier
The Global Forest Resources Assessment 2015 shows that deforestation has slowed and
afforestation has increased globally during 1990–2015. Planted forests have increasingly …

Nephrocalcinosis: molecular insights into calcium precipitation within the kidney

JA Sayer, G Carr, NL Simmons - Clinical science, 2004 - portlandpress.com
Nephrocalcinosis may be defined as a generalized increase in the calcium content of the
kidneys. This renal calcification may occur at a molecular, microscopic or macroscopic level …

Agriculture production as a major driver of the Earth system exceeding planetary boundaries

BM Campbell, DJ Beare, EM Bennett… - Ecology and society, 2017 - JSTOR
We explore the role of agriculture in destabilizing the Earth system at the planetary scale,
through examining nine planetary boundaries, or “safe limits”: land-system change, freshwater …

The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4

JA Sayer, EA Otto, JF O'Toole, G Nurnberg… - Nature …, 2006 - nature.com
The molecular basis of nephronophthisis 1 , the most frequent genetic cause of renal failure
in children and young adults, and its association with retinal degeneration and cerebellar …

Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin

EA Otto, B Loeys, H Khanna, J Hellemans, R Sudbrak… - Nature …, 2005 - nature.com
Nephronophthisis (NPHP) is the most frequent genetic cause of chronic renal failure in
children 1 , 2 , 3 . Identification of four genes mutated in NPHP subtypes 1–4 (refs. 4 – 9 ) has …

[HTML][HTML] Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling

M Chaki, R Airik, AK Ghosh, RH Giles, R Chen… - Cell, 2012 - cell.com
Nephronophthisis-related ciliopathies (NPHP-RC) are degenerative recessive diseases that
affect kidney, retina, and brain. Genetic defects in NPHP gene products that localize to cilia …

In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 …

B Chang, H Khanna, N Hawes, D Jimeno… - Human molecular …, 2006 - academic.oup.com
Centrosome- and cilia-associated proteins play crucial roles in establishing polarity and
regulating intracellular transport in post-mitotic cells. Using genetic mapping and positional …

[BOEK][B] Tropical deforestation and species extinction

TC Whitmore, JA Sayer - 1992 - Springer
Most animal and plant species inhabit tropical forests. Hence the interest in the effects of
tropical forest clearance on biological diversity. The book provides a conservationist's …

[HTML][HTML] Improved tropical forest management for carbon retention

FE Putz, PA Zuidema, MA Pinard, RGA Boot… - PLoS …, 2008 - journals.plos.org
Using reduced-impact timber-harvesting practices in legally logged tropical forests would
reduce global carbon emissions by 0.16 Gt/year at a modest cost and with little risk of" …