CONTEXT: In 2005, fusions between the androgen-regulated transmembrane protease
serine 2 gene, TMPRSS2, and E twenty-six (ETS) transcription factors were discovered in …

The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert
Panel identified and reviewed the available evidence for the ten most important areas of …

Although the routine use of serum PSA testing has undoubtedly increased prostate cancer
detection, one of its main drawbacks has been its lack of specificity, which results in a high …

Background: DD3 PCA3 is the most prostate cancer-specific gene described to date. To
assess the clinical utility of DD3 PCA3 a time-resolved fluorescence-based, quantitative RT-…

E-cadherin is a Ca 2+ -dependent cell adhesion molecule which plays an important role in
normal growth and development via mediation of homotypic, homophilic cell-cell interaction. …

Purpose: Early detection of prostate cancer can increase the curative success rate for prostate
cancer. We studied the diagnostic usefulness of TMPRSS2-ERG fusion transcripts as well …

… Schalken JA New perspectives in the treatment of prostate cancer. … Bussemakers MJG, Van
de Ven WJM, Debruyne FMJ, Schalken JA Identification of high mobility group protein I(Y) as …

We identified DD3 PCA3 as one of the most prostate cancer-specific genes at present (MJ
Bussemakers et al. Cancer Res., 59: 5975–5979, 1999). Consequently, DD3 PCA3 is an …

… Bringuier PP, Umbas R., Schaafsma HE, Karthaus HF, Debruyne FM, Schalken JA Decreased
E-… Bussemakers MJG, Van Bokhoven A., Tomita K., Jansen CFJ, Schalken JA Cadherin …

The common sequence variants that have recently been associated with cancer risk are
particular to a single cancer type or at most two. Following up on our genome-wide scan of …