Background Healthcare organisations face major challenges to keep healthcare accessible
and affordable. This requires them to transform and improve their performance. To do so, …

Purpose Callous–unemotional (CU) traits are currently viewed as the defining signs and
symptoms of juvenile psychopathy. It is unclear, however, whether CU traits have validity only in …

It is unclear whether the concepts and findings of the underlying neurobiology of adult
psychopathy apply to youths as well. If so, a life span approach to treatment should be taken. …

achtergrond Antipsychotica zijn effectieve geneesmiddelen die veel worden voorgeschreven
aan een grote groep patiënten. Echter, ze hebben veel bijwerkingen, die uiteindelijk …

Objective Recent trials have indicated positive effects of bumetanide in autism spectrum
disorder (ASD). We tested efficacy of bumetanide on core symptom domains using a single …

This study was designed to examine whether proactive and reactive aggression are meaningful
distinctions at the variable- and person-based level, and to determine their associated …

Typical antipsychotics have been reported to enlarge the caudate nucleus in schizophrenic
patients. The atypical antipsychotic, clozapine, is associated with a decrease in caudate size …

Despite the high level of interest in the use of machine learning (ML) and neuroimaging to
detect psychosis at the individual level, the reliability of the findings is unclear due to potential …

Advances in commercial wearable devices are increasingly facilitating the collection and
analysis of everyday physiological data. This article discusses the theoretical and practical …

Preparations for the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) are ongoing. Publication is planned in May 2013 and as part of the developmental …