The approach to paediatric drug dosing needs to be based on the physiological characteristics
of the child and the pharmacokinetic parameters of the drug. This review summarises the …

Transfer of automated laboratory data collected during routine clinical care from the laboratory
information system into a database format that enables linkage to other administrative (eg, …

Corticosteroids are potent antiinflammatory and immunosuppressive drugs, which are used
in the treatment of a wide range of medical disorders. During pregnancy, several …

OBJECTIVES: To investigate the association between antipsychotic drug use and risk of
pneumonia in elderly people. DESIGN: A nested case‐control analysis. SETTING: Data were …

Objective Liquid medicines are easy to swallow. However, they may have disadvantages,
such as a bad taste or refrigerated storage conditions. These disadvantages may be avoided …

Background and Objective Increasing numbers of women in childbearing years are treated
with antidepressants. Concerns regarding fetal exposure to medication has led to large …

Safe and effective paediatric pharmacotherapy requires careful evaluation of the type of drug
substance, the necessary dose and the age-appropriateness of the formulation. Generally, …

The availability of licensed paediatric drugs is lagging behind those for adults, and there is
a lack of safe formulations in suitable doses that children are able and willing to take. As a …

Aim: In the present, prospective study, the relation between the levels of midazolam, its two
active metabolites—1‐hydroxy‐midazolam (OH‐midazolam) and 1‐hydroxy‐midazolam‐…

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Children are entitled to safe,
efficacious, child and parent friendly (ie age‐appropriate) medicines. However, off‐label and …