Objective To assess the accuracy of the Wells rule for excluding deep vein thrombosis and
whether this accuracy applies to different subgroups of patients. Design Meta-analysis of …

COVID-19 is associated with a high incidence of thrombotic complications, which can be
explained by the complex and unique interplay between coronaviruses and endothelial cells, …

In persons with hemophilia, life expectancy is now approaching that of the general male
population, at least in countries that can afford regular replacement therapy with coagulation …

The classification of haemophilia originates from 1950s and has been adopted unchallengedly
by the ISTH in 2001. The aim of this study was: does the current classification compare …

Background— Serial ultrasonography is reliable for the diagnosis of deep venous thrombosis
in symptomatic patients, but the low prevalence of thrombosis in this group renders the …

Background— Patients with severe limb ischemia may not be eligible for conventional therapeutic
interventions. Pioneering clinical trials suggest that bone marrow–derived cell therapy …

Background: Low NT‐proBNP levels are associated with an uncomplicated course in patients
with pulmonary embolism (PE). The aim of this multicenter management study was to …

Background D-dimer testing to rule out deep vein thrombosis is less useful in older patients
because of a lower specificity. An age-adjusted D-dimer cut-off value increased the …

Because of an increased life expectancy, (age‐related) co‐morbidity is becoming a
common occurrence in haemophilia patients. In this review, haemophilia‐related and non‐…

Mortality due to ischemic heart disease in hemophilia patients is lower as compared to the
general male population. Differences in the prevalence of cardiovascular risk factors cannot …