Mirtazapine is the first noradrenergic and specific serotonergic antidepressant (‘NaSSA’). It
is rapidly and well absorbed from the gastrointestinal tract after single and multiple oral …

Background Local intramuscular administration of the antisense oligonucleotide PRO051 in
patients with Duchenne's muscular dystrophy with relevant mutations was previously …

Background: Gepirone, a 5-HT 1A receptor agonist, has been assessed for use in the
treatment of anxiety and depressive disorders. Azapirones, including gepirone, act to maintain …

Objective: To assess the efficacy and tolerability of the 5-HT1A agonist gepirone in extendedrelease
formulation (gepirone-ER) versus placebo in patients with major depressive disorder…

This study deals with the effects of [beta]-endorphin on blood pressure, heart rate, and
respiratory frequency in anesthetized and conscious rats after both peripheral and central …

Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA) with a
novel mode of action, which has recently been registered in a number of European countries. …

Pain sensitivity in Spontaneously Hypertensive Rats (SHR) and normotensive Wistar-Kyoto
controls (WKY) as well as in experimentally hypertensive Wistar rats has been studied. …

In two studies, the effects of the potentially interacting drugs mirtazapine and carbamazepine
on their pharmacokinetics have been investigated. Subjects were treated with …

Immunological and non-immunological injury induce as a result of the action of the enzyme
lipoxygenase the release of a series of arachidonic acid metabolites known as leukotrienes. …

An open-label, non-randomized, pilot study has been performed in inpatients in need of
treatment with an antipsychotic (risperidone) and an antidepressant (mirtazapine) with the …