Clinical pharmacokinetics of mirtazapine
CJ Timmer, JMA Sitsen, LP Delbressine - Clinical pharmacokinetics, 2000 - Springer
Mirtazapine is the first noradrenergic and specific serotonergic antidepressant (‘NaSSA’). It
is rapidly and well absorbed from the gastrointestinal tract after single and multiple oral …
is rapidly and well absorbed from the gastrointestinal tract after single and multiple oral …
[HTML][HTML] Systemic administration of PRO051 in Duchenne's muscular dystrophy
NM Goemans, M Tulinius… - … England Journal of …, 2011 - Mass Medical Soc
Background Local intramuscular administration of the antisense oligonucleotide PRO051 in
patients with Duchenne's muscular dystrophy with relevant mutations was previously …
patients with Duchenne's muscular dystrophy with relevant mutations was previously …
A review of the efficacy and tolerability of immediate-release and extended-release formulations of gepirone
DS Robinson, JMA Sitsen, M Gibertini - Clinical therapeutics, 2003 - Elsevier
Background: Gepirone, a 5-HT 1A receptor agonist, has been assessed for use in the
treatment of anxiety and depressive disorders. Azapirones, including gepirone, act to maintain …
treatment of anxiety and depressive disorders. Azapirones, including gepirone, act to maintain …
Gepirone extended-release: new evidence for efficacy in the treatment of major depressive disorder
AD Feiger, JF Heiser, RK Shrivastava… - Journal of Clinical …, 2003 - psychiatrist.com
Objective: To assess the efficacy and tolerability of the 5-HT1A agonist gepirone in extendedrelease
formulation (gepirone-ER) versus placebo in patients with major depressive disorder…
formulation (gepirone-ER) versus placebo in patients with major depressive disorder…
Observations on pain perception and hypertension in spontaneously hypertensive rats
JMA Sitsen, W Jong - … Hypertension. Part A: Theory and Practice, 1984 - Taylor & Francis
Pain sensitivity in Spontaneously Hypertensive Rats (SHR) and normotensive Wistar-Kyoto
controls (WKY) as well as in experimentally hypertensive Wistar rats has been studied. …
controls (WKY) as well as in experimentally hypertensive Wistar rats has been studied. …
Cardiovascular and respiratory effects of β-endorphin in anesthetized and conscious rats
JMA Sitsen, JM Van Ree… - Journal of Cardiovascular …, 1982 - journals.lww.com
This study deals with the effects of [beta]-endorphin on blood pressure, heart rate, and
respiratory frequency in anesthetized and conscious rats after both peripheral and central …
respiratory frequency in anesthetized and conscious rats after both peripheral and central …
Mirtazapine: clinical profile
JMA Sitsen, M Zivkov - Cns Drugs, 1995 - Springer
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA) with a
novel mode of action, which has recently been registered in a number of European countries. …
novel mode of action, which has recently been registered in a number of European countries. …
Leukotrienes, allergy and inflammation
FP Nijkamp, JMA Sitsen - Pharmaceutisch Weekblad, 1982 - Springer
Immunological and non-immunological injury induce as a result of the action of the enzyme
lipoxygenase the release of a series of arachidonic acid metabolites known as leukotrienes. …
lipoxygenase the release of a series of arachidonic acid metabolites known as leukotrienes. …
Drug-drug interaction studies with mirtazapine and carbamazepine in healthy male subjects
JMA Sitsen, FA Maris, CJ Timmer - European journal of drug metabolism …, 2001 - Springer
In two studies, the effects of the potentially interacting drugs mirtazapine and carbamazepine
on their pharmacokinetics have been investigated. Subjects were treated with …
on their pharmacokinetics have been investigated. Subjects were treated with …
Lack of drug interactions between mirtazapine and risperidone in psychiatric patients: a pilot study
AJM Loonen, CH Doorschot, M Oostelbos… - European …, 1999 - Elsevier
An open-label, non-randomized, pilot study has been performed in inpatients in need of
treatment with an antipsychotic (risperidone) and an antidepressant (mirtazapine) with the …
treatment with an antipsychotic (risperidone) and an antidepressant (mirtazapine) with the …