Subjective cognitive decline and rates of incident Alzheimer's disease and non–Alzheimer's disease dementia

RER Slot, SAM Sikkes, J Berkhof, H Brodaty… - Alzheimer's & …, 2019 - Elsevier
Introduction In this multicenter study on subjective cognitive decline (SCD) in community-based
and memory clinic settings, we assessed the (1) incidence of Alzheimer's disease (AD) …

Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes

R Janssen, L Bont, CLE Siezen… - Journal of Infectious …, 2007 - academic.oup.com
Background. Respiratory syncytial virus (RSV) is a common cause of severe lower
respiratory tract infection in infants. Only a proportion of children infected with RSV require …

Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect

AJ Monsuur, PIW Bakker, BZ Alizadeh, A Zhernakova… - Nature …, 2005 - nature.com
Celiac disease is probably the best-understood immune-related disorder. The disease presents
in the small intestine and results from the interplay between multiple genes and gluten, …

Plasma amyloid as prescreener for the earliest A lzheimer pathological changes

IMW Verberk, RE Slot, SCJ Verfaillie… - Annals of …, 2018 - Wiley Online Library
Objective We investigated the association of plasma amyloid beta (Abeta)40, Abeta42, and
total tau (tTau) with the presence of Alzheimer pathological changes in cognitively normal …

Impact of the COVID-19 outbreak on acute stroke care

LA Rinkel, JCM Prick, RER Slot, NMA Sombroek… - Journal of …, 2021 - Springer
Background and purpose There are concerns that the coronavirus disease 2019 (COVID-19)
outbreak negatively affects the quality of care for acute cardiovascular conditions. We …

ATN classification and clinical progression in subjective cognitive decline: The SCIENCe project

JL Ebenau, T Timmers, LMP Wesselman… - Neurology, 2020 - AAN Enterprises
Objective To investigate the relationship between the ATN classification system (amyloid,
tau, neurodegeneration) and risk of dementia and cognitive decline in individuals with …

Subjective Cognitive Impairment Cohort (SCIENCe): study design and first results

RER Slot, SCJ Verfaillie, JM Overbeek… - Alzheimer's research & …, 2018 - Springer
Background We aimed to describe the Subjective Cognitive Impairment Cohort (SCIENCe)
study design, to cross-sectionally describe participant characteristics, and to evaluate the …

Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study

A Lleó, D Alcolea, P Martínez-Lage, P Scheltens… - Alzheimer's & …, 2019 - Elsevier
Introduction Within-person trajectories of cerebrospinal fluid (CSF) biomarkers in
Alzheimer's disease (AD) are not well defined. Methods We included 467 subjects from the …

Surrogate model uncertainty in wind turbine reliability assessment

RMM Slot, JD Sørensen, B Sudret, L Svenningsen… - Renewable Energy, 2020 - Elsevier
Lowering the cost of wind energy entails the optimization of wind turbine material consumption
without compromising structural safety. Traditionally, wind turbines are designed by the …

How enterprise architecture improves the quality of IT investment decisions

M Van den Berg, R Slot, M van Steenbergen… - Journal of Systems and …, 2019 - Elsevier
According to literature, enterprise architecture (EA) is supposed to support IT investment
decision-making. However, it is not yet clear how EA can do that. The objective of this study is to …