Background. In recent years, resident cardiac progenitor cells have been identified in, and
isolated from the rodent heart. These cells show the potential to form cardiomyocytes, smooth …

Cardiomyocyte progenitor cell‐derived exosomes stimulate migration of endothelial cells -
Vrijsen - 2010 - Journal of Cellular and Molecular Medicine - Wiley Online Library Skip to …

Ischaemic heart disease and the heart failure that often results, remain the leading causes of
death and disability in Europe and worldwide. As such, in order to prevent heart failure and …

The Earth turns on its axis every 24 h; almost all life on the planet has a mechanism —
circadian rhythmicity — to anticipate the daily changes caused by this rotation. The molecular …

Heart failure is characterized by a debilitating decline in cardiac function 1 , and recent
clinical trial results indicate that improving the contractility of heart muscle cells by boosting …

Tissue engineering is emerging as a potential therapeutic approach to overcome limitations
of cell therapy, like cell retention and survival, as well as to mechanically support the …

Left ventricular (LV) remodeling leads to congestive heart failure and is a main determinant
of morbidity and mortality following myocardial infarction. Therapeutic options to prevent LV …

Objective— To improve regeneration of the injured myocardium, it is necessary to enhance
the intrinsic capacity of the heart to regenerate itself and/or replace the damaged tissue by …

Accumulating evidence indicatesthat programmed necrosis plays a critical role in cell death
during ischemia–reperfusion. Necrostatin-1 (Nec-1), a small molecule capable of inhibiting a …

To date, there is no suitable in vitro model to study human adult cardiac cell biology. Although
embryonic stem cells are able to differentiate into cardiomyocytes in vitro, the efficiency of …