Modern diagnosis of GERD: the Lyon Consensus

CP Gyawali, PJ Kahrilas, E Savarino, F Zerbib, F Mion… - Gut, 2018 - gut.bmj.com
Clinical history, questionnaire data and response to antisecretory therapy are insufficient to
make a conclusive diagnosis of GERD in isolation, but are of value in determining need for …

Chicago classification criteria of esophageal motility disorders defined in high resolution esophageal pressure topography1

AJ Bredenoord, M Fox, PJ Kahrilas… - …, 2012 - Wiley Online Library
Background The Chicago Classification of esophageal motility was developed to facilitate
the interpretation of clinical high resolution esophageal pressure topography (EPT) studies, …

Functional esophageal disorders

JP Galmiche, RE Clouse, A Balint, IJ Cook, PJ Kahrilas… - Gastroenterology, 2006 - Elsevier
Functional esophageal disorders represent processes accompanied by typical esophageal
symptoms (heartburn, chest pain, dysphagia, globus) that are not explained by structural …

What is measured in electrogastrography?

A Smout, EJ Van der Schee, JL Grashuis - Digestive diseases and …, 1980 - Springer
The object of this study was to elucidate what is actually measured in electrogastrography.
Comparison of gastric signals simultaneously recorded from serosal and cutaneous …

The Chicago Classification of esophageal motility disorders, v3. 0

PJ Kahrilas, AJ Bredenoord, M Fox… - …, 2015 - Wiley Online Library
Background The Chicago Classification ( CC ) of esophageal motility disorders, utilizing an
algorithmic scheme to analyze clinical high‐resolution manometry ( HRM ) studies, has …

The symptom-association probability: an improved method for symptom analysis of 24-hour esophageal pH data

BLAM Weusten, JMM Roelofs, LMA Akkermans… - Gastroenterology, 1994 - Elsevier
… Breumelhof R, Smout AJPM. The symptom sensitivity index: a valuable additional
parameter in 24-hour esophageal pH recording. Am J Gastroenterol 1991;86:160-164. …

Excess gastroesophageal reflux in patients with hiatus hernia is caused by mechanisms other than transient LES relaxations

MA Van Herwaarden, M Samsom, AJPM Smout - Gastroenterology, 2000 - Elsevier
Background & Aims: Esophageal acid exposure is higher in gastroesophageal reflux disease
(GERD) patients with hiatus hernia than in those without. We investigated the effect of a …

Abnormal clearance of exogenous acid and increased acid sensitivity of the proximal duodenum in dyspeptic patients

M Samsom, MAMT Verhagen… - Gastroenterology, 1999 - Elsevier
Background & Aims: Although acid is likely to play a role in the genesis of symptoms in
dyspeptic patients, most studies have failed to show an increase in gastric acid secretion. The …

Symptomatic reflux disease: the present, the past and the future

G Boeckxstaens, HB El-Serag, AJPM Smout… - Gut, 2014 - gut.bmj.com
The worldwide incidence of GORD and its complications is increasing along with the
exponentially increasing problem of obesity. Of particular concern is the relationship between …

Disturbed solid-phase gastric emptying in functional dyspepsia (a meta-analysis)

AO Quarter, NJ De Wit, AC Lodder, ME Numans… - Digestive diseases and …, 1998 - Springer
Functional dyspepsia is a common disorder witha diverse pathophysiological background,
but the role ofmotility disorders in functional dyspepsia remainsunclear. We aimed to quantify …