Abstract Information on protein–protein interactions is still mostly limited to a small number
of model organisms, and originates from a wide variety of experimental and computational …

A systematic comparison of nine bacterial and archaeal genomes reveals a low level of
gene-order (and operon architecture) conservation. Nevertheless, a number of gene pairs are …

Highlights • bZIPs are evolutionarily conserved eukaryotic transcription factors. • The
Arabidopsis bZIP family consists of 78 members classified into 13 groups. • bZIPs perform a …

Anaerobic ammonium oxidation (anammox) has become a main focus in oceanography
and wastewater treatment 1 , 2 . It is also the nitrogen cycle's major remaining biochemical …

Bifidobacteria are Gram-positive prokaryotes that naturally colonize the human gastrointestinal
tract (GIT) and vagina. Although not numerically dominant in the complex intestinal …

Functional links between proteins can often be inferred from genomic associations between
the genes that encode them: groups of genes that are required for the same function tend to …

A full description of a protein's function requires knowledge of all partner proteins with which
it specifically associates. From a functional perspective, ‘association’ can mean direct …

Comprehensive protein–protein interaction maps promise to reveal many aspects of the
complex regulatory network underlying cellular function. Recently, large-scale approaches have …

The repeated occurrence of genes in each other’s neighbourhood on genomes has been
shown to indicate a functional association between the proteins they encode. Here we …

Species phylogenies derived from comparisons of single genes are rarely consistent with
each other, due to horizontal gene transfer 1, unrecognized paralogy and highly variable rates …