The biogenesis and functions of exosomes
W Stoorvogel, MJ Kleijmeer, HJ Geuze, G Raposo - Traffic, 2002 - Wiley Online Library
Exosomes are membrane vesicles with a diameter of 40–100 nm that are secreted by many
cell types into the extracellular milieu. They correspond to the internal vesicles of an …
cell types into the extracellular milieu. They correspond to the internal vesicles of an …
Extracellular vesicles: exosomes, microvesicles, and friends
G Raposo, W Stoorvogel - Journal of Cell Biology, 2013 - rupress.org
Cells release into the extracellular environment diverse types of membrane vesicles of
endosomal and plasma membrane origin called exosomes and microvesicles, respectively. …
endosomal and plasma membrane origin called exosomes and microvesicles, respectively. …
Biological properties of extracellular vesicles and their physiological functions
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
Proteomic and biochemical analyses of human B cell-derived exosomes: potential implications for their function and multivesicular body formation
R Wubbolts, RS Leckie, PTM Veenhuizen… - Journal of Biological …, 2003 - ASBMB
Exosomes are 60–100-nm membrane vesicles that are secreted into the extracellular milieu
as a consequence of multivesicular body fusion with the plasma membrane. Here we …
as a consequence of multivesicular body fusion with the plasma membrane. Here we …
B lymphocytes secrete antigen-presenting vesicles.
G Raposo, HW Nijman, W Stoorvogel… - The Journal of …, 1996 - rupress.org
Antigen-presenting cells contain a specialized late endocytic compartment, MIIC (major
histocompatibility complex [MHC] class II-enriched compartment), that harbors newly …
histocompatibility complex [MHC] class II-enriched compartment), that harbors newly …
Topography of glycosylation
HT Haigler, JA McKanna, S Cohen, S Felder, K Miller… - J. Cell Biol, 1979 - cell.com
FOUR DISTINCT TYPES of glycosylation are known to occur in the endoplasmic reticulum (ER)
of eukaryotic cells:(1) N-linked glycosylation of proteins involves the addition of a …
of eukaryotic cells:(1) N-linked glycosylation of proteins involves the addition of a …
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into
their microenvironment. Recent studies have elucidated the role of EVs in intercellular …
their microenvironment. Recent studies have elucidated the role of EVs in intercellular …
Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes
JM Escola, MJ Kleijmeer, W Stoorvogel… - Journal of Biological …, 1998 - ASBMB
Association of major histocompatibility complex (MHC) class II molecules with peptides
occurs in a series of endocytic vacuoles, termed MHC class II-enriched compartments (MIICs). …
occurs in a series of endocytic vacuoles, termed MHC class II-enriched compartments (MIICs). …
Endothelial cells require miR-214 to secrete exosomes that suppress senescence and induce angiogenesis in human and mouse endothelial cells
BWM van Balkom, OG De Jong, M Smits… - Blood, The Journal …, 2013 - ashpublications.org
Signaling between endothelial cells, endothelial progenitor cells, and stromal cells is crucial
for the establishment and maintenance of vascular integrity and involves exosomes, among …
for the establishment and maintenance of vascular integrity and involves exosomes, among …
Exosome: from internal vesicle of the multivesicular body to intercellular signaling device
K Denzer, MJ Kleijmeer, HFG Heijnen… - Journal of cell …, 2000 - journals.biologists.com
Exosomes are small membrane vesicles that are secreted by a multitude of cell types as a
consequence of fusion of multivesicular late endosomes/lysosomes with the plasma …
consequence of fusion of multivesicular late endosomes/lysosomes with the plasma …