Gebruikersprofielen voor "Storm, G. "
![]() | Gert StormGeverifieerd e-mailadres voor uu.nl Geciteerd door 57605 |
Theranostic nanomedicine
Nanomedicine formulations aim to improve the biodistribution and the target site
accumulation of systemically administered (chemo)therapeutic agents. Many different types of …
accumulation of systemically administered (chemo)therapeutic agents. Many different types of …
Endosomal escape pathways for delivery of biologicals
Despite continuous improvements in delivery systems, the development of methods for
efficient and specific delivery of targeted therapeutic agents still remains an issue in biological …
efficient and specific delivery of targeted therapeutic agents still remains an issue in biological …
Drug targeting to tumors: principles, pitfalls and (pre-) clinical progress
Many different systems and strategies have been evaluated for drug targeting to tumors over
the years. Routinely used systems include liposomes, polymers, micelles, nanoparticles …
the years. Routinely used systems include liposomes, polymers, micelles, nanoparticles …
Specific targeting with poly (ethylene glycol)-modified liposomes: coupling of homing devices to the ends of the polymeric chains combines effective target binding …
G Blume, G Cevc, M Crommelin… - … et Biophysica Acta (BBA …, 1993 - Elsevier
One possibility for bringing drugs to their specific targets is to use the drug-laden liposomes
that have been made target-specific by the attachment of appropriate proteins. Such ‘directed…
that have been made target-specific by the attachment of appropriate proteins. Such ‘directed…
Accelerated blood clearance and altered biodistribution of repeated injections of sterically stabilized liposomes
Sterically stabilized liposomes are considered promising carriers of therapeutic agents because
they can facilitate controlled release of the drugs, thereby reducing drug-related toxicity …
they can facilitate controlled release of the drugs, thereby reducing drug-related toxicity …
[HTML][HTML] Lymphatic uptake and biodistribution of liposomes after subcutaneous injection.: II. Influence of liposomal size, lipid composition and lipid dose
C Oussoren, J Zuidema, DJA Crommelin… - Biochimica et Biophysica …, 1997 - Elsevier
The present paper reports on the results of a systematic study on liposome variables
potentially affecting lymphatic disposition and biodistribution of liposomes after sc injection. …
potentially affecting lymphatic disposition and biodistribution of liposomes after sc injection. …
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
RM Schiffelers, A Ansari, J Xu, Q Zhou… - Nucleic acids …, 2004 - academic.oup.com
Potent sequence selective gene inhibition by siRNA ‘targeted’ therapeutics promises the
ultimate level of specificity, but siRNA therapeutics is hindered by poor intracellular uptake, …
ultimate level of specificity, but siRNA therapeutics is hindered by poor intracellular uptake, …
Quantum dots with a paramagnetic coating as a bimodal molecular imaging probe
WJM Mulder, R Koole, RJ Brandwijk, G Storm… - Nano …, 2006 - ACS Publications
MRI detectable and targeted quantum dots were developed. To that aim, quantum dots were
coated with paramagnetic and pegylated lipids, which resulted in a relaxivity, r 1 , of nearly …
coated with paramagnetic and pegylated lipids, which resulted in a relaxivity, r 1 , of nearly …
Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin
Angiogenesis is a key process in the growth and metastasis of a tumor. Disrupting this
process is considered a promising treatment strategy. Therefore, a drug delivery system …
process is considered a promising treatment strategy. Therefore, a drug delivery system …
Factors affecting the accelerated blood clearance of polyethylene glycol-liposomes upon repeated injection
P Laverman, MG Carstens, OC Boerman… - … of Pharmacology and …, 2001 - ASPET
Previously, we showed that long-circulating polyethylene glycol (PEG)-liposomes are cleared
rapidly from the circulation when injected repeatedly in the same animal. In this article, we …
rapidly from the circulation when injected repeatedly in the same animal. In this article, we …