OR the past 10 years, there has been substantial progress in the field of peroxisome biogenesis.
One key to this progress has been the use of genetic approaches in a wide variety of …

The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites
required for and formed during fatty acid β-oxidation. To communicate with the cytoplasm and …

Peroxisomes belong to the ubiquitous organelle repertoire of eukaryotic cells. They contribute
to cellular metabolism in various ways depending on species, but a consistent feature is …

How peroxisomes are formed in eukaryotic cells is unknown but important for insight into a
variety of diseases. Both human and yeast cells lacking peroxisomes due to mutations in …

We investigated how NADH generated during peroxisomal beta‐oxidation is reoxidized to
NAD+ and how the end product of beta‐oxidation, acetyl‐CoA, is transported from …

Peroxisomes of Saccharomyces cerevisiae are the exclusive site of fatty acid beta‐oxidation.
We have found that fatty acids reach the peroxisomal matrix via two independent pathways. …

We describe a genome-wide characterization of mRNA transcript levels in yeast grown on
the fatty acid oleate, determined using Serial Analysis of Gene Expression (SAGE). …

Excised group II introns in yeast mitochondria appear as covalently closed circles under the
electron microscope. We show that these circular molecules are branched and resemble the …

In vivo time-lapse microscopy reveals that the number of peroxisomes in Saccharomyces
cerevisiae cells is fairly constant and that a subset of the organelles are targeted and …

As a rule, organelles in eukaryotic cells can derive only from pre-existing organelles.
Peroxisomes are unique because they acquire their lipids and membrane proteins from the …