Major insights into the phylogenetic distribution, biochemistry, and evolutionary significance
of organelles involved in ATP synthesis (energy metabolism) in eukaryotes that thrive in …

Biochemistry textbooks depict mitochondria as oxygen-dependent organelles, but many
mitochondria can produce ATP without using any oxygen. In fact, several other types of …

Although parasitic helminths are a very heterogeneous group of organisms, they share many
interesting properties in their energy metabolism. In certain stages of their life cycle, they all …

Schistosome infections are characterized by prominent T cell hyporesponsiveness during
the chronic stage of infection. We found that schistosome-specific phosphatidylserine (PS) …

Hydrogenosomes are organelles that produce ATP and hydrogen 1 , and are found in various
unrelated eukaryotes, such as anaerobic flagellates, chytridiomycete fungi and ciliates 2 . …

The tegumental outer-surface of schistosomes is a unique double membrane structure that
is of crucial importance for modulation of the host response and parasite survival. Although …

Many lower eukaryotes can survive anaerobic conditions via a fermentation pathway that
involves the use of the reduction of endogenously produced fumarate as electron sink. This …

Schistosoma mansoni is a parasitic worm that lives in the blood vessels of its host. We mapped
the S. mansoni tegumental outer-surface structure proteome by 1D SDS-PAGE and LC−…

Although various members of the family Trypanosomatidae generate energy in a similar way,
fundamental differences also exist and are not always recognized. In this review, Louis …

Hydrogenosome-containing anaerobic protists, such as the trichomonads, produce large
amounts of acetate by an acetate:succinate CoA transferase (ASCT)/succinyl CoA synthetase …