Dogs can be grouped into two distinct types of breed based on the predisposition to
chondrodystrophy, namely, non-chondrodystrophic (NCD) and chondrodystrophic (CD). In addition …

Intervertebral disc (IVD) degeneration is common in dogs and can give rise to a number of
diseases, such as IVD herniation, cervical spondylomyelopathy, and degenerative …

Lower back pain (LBP) occurs in 80% of adults in their lifetime; resulting in LBP being one
of the biggest causes of disability worldwide. Chronic LBP has been linked to the …

Introduction Early degeneration of the intervertebral disc (IVD) involves a change in cellular
differentiation from notochordal cells (NCs) in the nucleus pulposus (NP) to chondrocyte-like …

Pain due to spontaneous intervertebral disc (IVD) disease is common in dogs. In chondrodystrophic
(CD) dogs, IVD disease typically develops in the cervical or thoracolumbar spine at …

Background Intervertebral disc (IVD) disease is a common spinal disorder in dogs and
degeneration and inflammation are significant components of the pathological cascade. Only …

Background Transsphenoidal hypophysectomy is one of the treatment strategies in the
comprehensive management of dogs with pituitary‐dependent hypercortisolism ( PDH ). …

Plasma concentrations of the main vitamin D 3 metabolites (ie, 25(OH)D 3 , 1,25(OH) 2 D 3 ,
and 24,25(OH) 2 D 3 ) were measured in 14 weeks old large- and small-breed dogs (adult …

The notochordal cell (NC) of the nucleus pulposus (NP) is considered a potential NP progenitor
cell, and early intervertebral disk (IVD) degeneration involves replacement of NCs by …

During intervertebral disc (IVD) maturation, the main cell type shifts from notochordal cells (NCs)
to chondrocytelike cells (CLCs). NCs secrete factors with regenerative potential, making …