Peripheral arterial disease
SM Conte, PR Vale - Heart, Lung and Circulation, 2018 - Elsevier
Peripheral arterial disease (PAD) affects 15% of the Australian population and is a powerful
and serious predictor of cardiovascular mortality yet continues to be under-recognised and …
and serious predictor of cardiovascular mortality yet continues to be under-recognised and …
Two decades of marine biotoxin monitoring in bivalves from Portugal (1986–2006): A review of exposure assessment
P Vale, MJ Botelho, SM Rodrigues, SS Gomes… - Harmful Algae, 2008 - Elsevier
Foodborne outbreaks attributed to marine biotoxins were first reported in Portugal in 1946.
A regular monitoring programme was implemented in 1986 for PSP, in 1987 for DSP and in …
A regular monitoring programme was implemented in 1986 for PSP, in 1987 for DSP and in …
Assessment of risks associated with cardiovascular gene therapy in human subjects
JM Isner, PR Vale, JF Symes, DW Losordo - Circulation research, 2001 - Am Heart Assoc
Clinical trials of cardiovascular gene therapy, whether using viral (53%) or nonviral (47%)
vectors, have thus far disclosed no evidence indicative of inflammatory or other complications, …
vectors, have thus far disclosed no evidence indicative of inflammatory or other complications, …
Gene Therapy for Myocardial Angiogenesis: Initial Clinical Results With Direct Myocardial Injection of phVEGF165 as Sole Therapy for Myocardial Ischemia
DW Losordo, PR Vale, JF Symes, CH Dunnington… - Circulation, 1998 - Am Heart Assoc
Background—We initiated a phase 1 clinical study to determine the safety and bioactivity of
direct myocardial gene transfer of vascular endothelial growth factor (VEGF) as sole therapy …
direct myocardial gene transfer of vascular endothelial growth factor (VEGF) as sole therapy …
Phase 1/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with …
DW Losordo, PR Vale, RC Hendel, CE Milliken… - Circulation, 2002 - Am Heart Assoc
Background— This phase 1/2 study investigated the safety of percutaneous catheter-based
gene transfer of naked plasmid DNA encoding for vascular endothelial growth factor 2 (…
gene transfer of naked plasmid DNA encoding for vascular endothelial growth factor 2 (…
Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease
JF Symes, DW Losordo, PR Vale, KG Lathi… - The Annals of thoracic …, 1999 - Elsevier
Background. Patients presenting with medically intractable angina who have undergone
previous coronary bypass (CABG) and/or percutaneous revascularization procedures are …
previous coronary bypass (CABG) and/or percutaneous revascularization procedures are …
VEGF gene transfer mobilizes endothelial progenitor cells in patients with inoperable coronary disease
C Kalka, H Tehrani, B Laudenberg, PR Vale… - The Annals of thoracic …, 2000 - Elsevier
Background. Direct transfection of ischemic myocardium with naked plasmid DNA encoding
for vascular endothelial growth factor-165 (VEGF 165 ) has been shown to mobilize …
for vascular endothelial growth factor-165 (VEGF 165 ) has been shown to mobilize …
Left Ventricular Electromechanical Mapping to Assess Efficacy of phVEGF165 Gene Transfer for Therapeutic Angiogenesis in Chronic Myocardial Ischemia
PR Vale, DW Losordo, CE Milliken, M Maysky… - Circulation, 2000 - Am Heart Assoc
Background—NOGA left ventricular (LV) electromechanical mapping (EMM) can be used to
distinguish among infarcted, ischemic, and normal myocardium. We investigated the use of …
distinguish among infarcted, ischemic, and normal myocardium. We investigated the use of …
Randomized, single-blind, placebo-controlled pilot study of catheter-based myocardial gene transfer for therapeutic angiogenesis using left ventricular …
PR Vale, DW Losordo, CE Milliken, MC McDonald… - Circulation, 2001 - Am Heart Assoc
Background—Catheter-based myocardial gene transfer (GTx) has not been previously tested
in human subjects. Accordingly, we performed a pilot study to investigate the feasibility and …
in human subjects. Accordingly, we performed a pilot study to investigate the feasibility and …
South Africa and the African renaissance
P Vale, S Maseko - International affairs, 1998 - academic.oup.com
This article addresses the question of the new South Africa's relationships with other countries
in Africa in the context of the idea of an ‘African Renaissance’ which has recently gained …
in Africa in the context of the idea of an ‘African Renaissance’ which has recently gained …
