Reduced glutamine synthetase in hippocampal areas with neuron loss in temporal lobe epilepsy

WS Van der Hel, RGE Notenboom, IWM Bos… - Neurology, 2005 - AAN Enterprises
Background: Increased levels of glutamate have been reported in the epileptogenic
hippocampus of patients with temporal lobe epilepsy (TLE). This sustained increase, which may …

Effect of valproic acid on sodium currents in cortical neurons from patients with pharmaco-resistant temporal lobe epilepsy

M Vreugdenhil, CWM van Veelen, PC van Rijen… - Epilepsy research, 1998 - Elsevier
In a selected group of temporal lobe epilepsy patients with seizures refractory to pharmacological
treatment, pharmacological seizure control can be attained by surgical resection of the …

MR contribution in surgery of epilepsy

LC Meiners, J Valk, GH Jansen, CWM Van Veelen - European Radiology, 1999 - Springer
The contribution of MR imaging in patients with drug-resistant epilepsy considered for surgical
therapy is discussed. In this review we focus on: (a) focal abnormalities (mesial temporal …

Regional brain glucose metabolism in patients with complex partial seizures investigated by intracranial EEG

B Sadzot, RMC Debets, P Maquet, CWM Van Veelen… - Epilepsy research, 1992 - Elsevier
We performed interictal 18 F-2-fluoro-2-deoxy-d-glucose positron emission tomography ( 18
FDG-PET) studies in 57 patients with complex partial epilepsy (CPE), not controlled by …

Quantitative Analysis of 18/FDG-PET in the Presurgical Evaluation of Patients Suffering from Refractory Partial Epilepsy: Comparison with CT, MRI, and Combined …

RMC Debets, CWM Van Veelen, P Maquet… - … Aspects of Epilepsy …, 1990 - Springer
CT, MRI, 18/FDG-PET and Depth. EEG, performed with subdural and depth electrodes were
part of the presurgical evaluation in 22 patients. Statistical analysis of 18/FDG-PET was …

Inhibitors of protein tyrosine phosphorylation reduce the proliferation of two human glioma cell lines

PA Weernink, E Verheul, E Kerkhof… - …, 1996 - journals.lww.com
EPIDERMAL GROWTH FACTOR (EGF) and platelet-derived growth factor (PDGF) are
suggested to be involved in the proliferation of human gliomas. We examined the effects of these …

Mini‐Review: Morphological changes in the human epileptogenic hippocampus

EA Proper, G Hoogland… - Neuroscience …, 2001 - Wiley Online Library
The availability of surgical tissue from epilepsy patients and the development of different
animal models have increased our knowledge about the morphological changes in the …

Is 11C-flumazenil PET superior to 18FDG PET and 123I-iomazenil SPECT in presurgical evaluation of temporal lobe epilepsy?

RM Debets, B Sadzot, JW Van Isselt… - Journal of Neurology …, 1997 - jnnp.bmj.com
OBJECTIVE: To determine the contribution of 18FDG PET, 11C-flumazenil PET, and 123I-iomazenil
SPECT to the presurgical evaluation of patients with medically intractable complex …

[CITAAT][C] Brief Communications-Language Area Localization with Three-Dimensional Functional Magnetic Resonance Imaging Matches Intrasulcal Electrostimulation …

GJM Rutten, PC Rijen… - Annals of …, 1999 - [Boston, Little, Brown and Co.]

[CITAAT][C] The Pyruvate Kinase Isoenzyme Shift in Human Gliomas: Useful in the Treatment of Gliomas?

CWM Veelen, GEJ Staal - Neuro Orthopedics, 1994 - Wien; New York: Springer-Verlag …