Fatty acid hydroperoxide lyase: a plant cytochrome P450 enzyme involved in wound healing and pest resistance
MA Noordermeer, GA Veldink… - Chembiochem, 2001 - Wiley Online Library
Plants continuously have to defend themselves against life‐threatening events such as
drought, mechanical damage, temperature stress, and potential pathogens. Nowadays, more …
drought, mechanical damage, temperature stress, and potential pathogens. Nowadays, more …
Acute neuronal injury, excitotoxicity, and the endocannabinoid system
The endocannabinoid system is a valuable target for drug discovery, because it is involved
in the regulation of many cellular and physiological functions. The endocannabinoid system …
in the regulation of many cellular and physiological functions. The endocannabinoid system …
Plant lipoxygenases
GA Veldink, JFG Vliegenthart, J Boldingh - … in the Chemistry of Fats and …, 1977 - Elsevier
PLANT LIPOXYGENASES Page 1 PLANT LIPOXYGENASES GA VELDINK, JFG
VLIEGENTHART and J. BOLDINGH Uniorrsiry of Urrecht. Laboratory for Orgatlic Chemistry …
VLIEGENTHART and J. BOLDINGH Uniorrsiry of Urrecht. Laboratory for Orgatlic Chemistry …
Neuroprotection by Δ9-tetrahydrocannabinol, the main active compound in marijuana, against ouabain-induced in vivo excitotoxicity
M Van der Stelt, WB Veldhuis, PR Bär… - Journal of …, 2001 - Soc Neuroscience
Excitotoxicity is a paradigm used to explain the biochemical events in both acute neuronal
damage and in slowly progressive, neurodegenerative diseases. Here, we show in a …
damage and in slowly progressive, neurodegenerative diseases. Here, we show in a …
Demonstration by EPR spectroscopy of the functional role of iron in soybean lipoxygenase-1.
JJ De Groot, GA Veldink, JF Vliegenthart… - … et biophysica acta, 1975 - europepmc.org
1. The EPR spectrum at 15 degrees K of soybean lipoxygenase-1 in borate buffer pH 9.0
has been studied in relation to the presence of substrate (linoleic acid), product (13-L-…
has been studied in relation to the presence of substrate (linoleic acid), product (13-L-…
Anandamide hydrolysis by human cells in culture and brain
M Maccarrone, M van der Stelt, A Rossi… - Journal of Biological …, 1998 - ASBMB
Anandamide (arachidonylethanolamide; AnNH) has important neuromodulatory and
immunomodulatory activities. This lipid is rapidly taken up and hydrolyzed to arachidonate and …
immunomodulatory activities. This lipid is rapidly taken up and hydrolyzed to arachidonate and …
Exogenous anandamide protects rat brain against acute neuronal injury in vivo
M Van der Stelt, WB Veldhuis… - Journal of …, 2001 - Soc Neuroscience
The endocannabinoid anandamide [N-arachidonoylethanolamine (AEA)] is thought to function
as an endogenous protective factor of the brain against acute neuronal damage. However…
as an endogenous protective factor of the brain against acute neuronal damage. However…
Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: role of vanilloid receptors and lipoxygenases
WB Veldhuis, M Van der Stelt… - Journal of …, 2003 - Soc Neuroscience
Type 1 vanilloid receptors (VR 1 ) have been identified recently in the brain, in which they
serve as yet primarily undetermined purposes. The endocannabinoid anandamide (AEA) and …
serve as yet primarily undetermined purposes. The endocannabinoid anandamide (AEA) and …
Oxygenated metabolites of anandamide and 2-arachidonoylglycerol: conformational analysis and interaction with cannabinoid receptors, membrane transporter, and …
M van der Stelt, JA van Kuik, M Bari… - Journal of medicinal …, 2002 - ACS Publications
This study was aimed at finding structural requirements for the interaction of the acyl chain
of endocannabinoids with cannabinoid receptors, membrane transporter protein, and fatty …
of endocannabinoids with cannabinoid receptors, membrane transporter protein, and fatty …
Emerging trade‐offs–impact of photoprotectants (PsbS, xanthophylls, and vitamin E) on oxylipins as regulators of development and defense
B Demmig‐Adams, CM Cohu, V Amiard… - New …, 2013 - Wiley Online Library
This review summarizes evidence for a mechanistic link between plant photoprotection and
the synthesis of oxylipin hormones as regulators of development and defense. Knockout …
the synthesis of oxylipin hormones as regulators of development and defense. Knockout …