Numerous studies investigating cisplatin ototoxicity in animals have been performed, but it
is difficult to derive a clear dose–effect relation from these studies. The degree of cisplatin-…

Sera from 76 patients with a clinical diagnosis of idiopathic rapidly progressive sensorineural
hearing loss (SNHL) (n = 15), sudden deafness (n = 31) and with other etiologies of their …

The objective of this study was to evaluate, during a long-term follow-up period, the results of
revision surgery for chronic otitis media with or without cholesteatoma. Intact canal wall and …

Cisplatin is frequently used in the treatment of various forms of malignancies. Its therapeutic
efficacy, however, is limited by the occurrence of sensorineural hearing loss. Little is known …

University of Groningen histophysiology and electron microscopy of the immune response
Veldman, Jan Edze Page 1 University of Groningen histophysiology and electron microscopy …

An immune‐complex mediated form of autoimmune disease is described with the inner ear
as one of its target organs. Around 40 dB bilateral sensorineural hearing loss improved on …

The ultrastructural distribution of gentamicin in the cochlea was investigated immunocytochemically.
Specific labeling was restricted to the organ of Corti, in particular to the outer and …

Since 1979, when McCabe first described a pattern of bilateral sensorineural hearing loss (SNHL)
characterized by a rapid progression over days to weeks, the postulated autoimmune …

The influence of different fixation methods and of various primary fixatives on the ultrastructural
preservation of guinea pig cochlear tissues was investigated. No differences in fixation …

The progress of sensorineural hearing loss (SNHL) in patients with cochlear otosclerosis was
compared for 19 patients treated with fluoride for 1-5 years and 22 untreated controls. CT …