Science and technology development have become critical instruments in the public policy
arena given their demonstrated impact on economic progress. As a consequence, a vast …

In November 1982, epidemiologic data were collected in a unique, large scale, population-based
survey on sports injuries in school-aged children living in Holland. A total of 7,468 …

Background More than a decade ago, a mammography screening programme for women
aged 50–69 years was initiated in the Netherlands. Our aim was to assess the effect of this …

Obesity results from the interaction of genetic and environmental factors. To search for sequence
variants that affect variation in two common measures of obesity, weight and body mass …

Adult human height is one of the classical complex human traits 1 . We searched for sequence
variants that affect height by scanning the genomes of 25,174 Icelanders, 2,876 Dutch, …

The transition from acute to chronic low back pain (LBP) is influenced by many interacting
factors. Pain-related fear, as measured by the Tampa Scale for Kinesiophobia (TSK) and the …

To assess the potential of breast-conserving treatment for ductal carcinoma in situ (DCIS),
82 mastectomy specimens were studied by Egan's serial subgross method. 42 (51%) of the …

Background Charles Bonnet's Syndrome (CBS), characterised by the presence of complex
visual hallucinations in psychologically normal people, was considered for a long time to be …

The thermodynamical efficiency of heat engines such as gasturbines and diesel engines
can be improved by the application of an increased combustion temperature. To protect the …

Background: A later menopause has been associated with a decreased cardiovascular risk
but with an increased risk for breast and endometrial cancer. The net effect on mortality is …