Trimethylated chitosan as polymeric absorption enhancer for improved peroral delivery of peptide drugs

SM Van der Merwe, JC Verhoef… - European journal of …, 2004 - Elsevier
The absorption enhancing effects of chitosan and its derivatives have been intensively studied
in recent years. It has been shown that these compounds are potent absorption enhancers…

Pathophysiological effects of endotoxins in ruminants: 2. Metabolic aspects

JACM Lohuis, JHM Verheijden, C Burvenich… - Veterinary …, 1988 - Taylor & Francis
Metabolic disturbances following intravenous and intramammary administration of endotoxins
in ruminants are described. In contrast to the similarity in response of blood biochemical …

Mystery swine disease in The Netherlands: the isolation of Lelystad virus

G Wensvoort, C Terpstra, JMA Pol, EA Ter Laak… - Veterinary …, 1991 - Taylor & Francis
In early 1991, the Dutch pig‐industry was struck by the so‐called mystery swine disease.
Large‐scale laboratory investigations were undertaken to search for the etiological agent. We …

Effect of fermented feed on the microbial population of the gastrointestinal tracts of pigs

RL van Winsen, BAP Urlings, LJA Lipman… - Applied and …, 2001 - Am Soc Microbiol
An in vivo experiment was performed with pigs to study the inhibitory effect of fermented feed
on the bacterial population of the gastrointestinal tract. Results demonstrated a significant …

A review of porcine reproductive and respiratory syndrome virus in Dutch breeding herds: population dynamics and clinical relevance

G Nodelijk, M Nielen, MCM De Jong… - Preventive veterinary …, 2003 - Elsevier
Understanding the spread of porcine reproductive and respiratory syndrome virus (PRRSV)
in pig populations is essential to the development of effective PRRS prevention and control …

Effect of maternally derived antibodies on the clinical signs and immune response in pigs after primary and secondary infection with an influenza H1N1 virus

WLA Loeffen, PP Heinen, ATJ Bianchi… - Veterinary immunology …, 2003 - Elsevier
The aim of this study was to determine the role of maternally derived antibodies (MDA) against
an influenza H1N1 virus in the clinical protection of piglets and especially their effect on …

New GnRH-like peptide construct to optimize efficient immunocastration of male pigs by immunoneutralization of GnRH

HB Oonk, JA Turkstra, WMM Schaaper, JHF Erkens… - Vaccine, 1998 - Elsevier
Castration of male pigs is routinely performed in order to prevent the occurrence of boar taint
in pig carcasses. However, boar taint can also be eliminated by immunological castration …

Evaluation of optimal age at first conception in gilts from data collected in commercial swine herds

YH Schukken, J Buurman, RBM Huirne… - Journal of animal …, 1994 - academic.oup.com
The purpose of this study was to find the economically optimal period of first conception in
gilts, addressing the issues of lifetime reproductive performance and expected herd life. A …

Intermittent suckling: Effects on piglet and sow performance before and after weaning

WI Kuller, NM Soede… - Journal of Animal …, 2004 - academic.oup.com
An experiment was conducted to study effects of intermittent suckling on creep feed intake
and weight gain of litters. Loss of weight and backfat during lactation, as well as reproductive …

Intestinal absorption of octreotide using trimethyl chitosan chloride: studies in pigs

M Thanou, JC Verhoef, JHM Verheijden… - Pharmaceutical …, 2001 - Springer
Purpose. To investigate the enhancing effect of trimethyl chitosan chloride (TMC) on the enteral
absorption of octreotide and to delineate the required doses of both TMC and peptide in …