Regulation of translation initiation factors by signal transduction

M Kleijn, GC Scheper, HO Voorma… - European journal of …, 1998 - Wiley Online Library
Regulation of eukaryotic translation initiation is a process that requires collaboration between
multiple proteins. The cap‐binding factor eukaryotic initiation factor (eIF)4E, its binding …

Basepairing with 18S ribosomal RNA in internal initiation of translation

GC Scheper, HO Voorma, AAM Thomas - FEBS letters, 1994 - Elsevier
In concert with the translation initiation factors ‘trans-acting’ factors function specifically
during internal initiation on picornaviral mRNAs. Of these trans-acting factors, two have been …

Initiation of eukaryotic protein synthesis

AAM Thomas, R Benne, HO Voorma - FEBS letters, 1981 - Elsevier
The initiation of protein synthesis is defined as the sequence of events, which leads to an 80
S. MettRNA. mRNA complex. Several non-ribosomal proteins are required for the formation …

Vector design for optimal protein expression

AW van der Velden, HO Voorma, AAM Thomas - Biotechniques, 2001 - Future Science
Many DNA constructs are generated for protein expression studies. Translational properties
and mRNA stability are crucial aspects that have to be accounted for during DNA …

Measles virus-specific human T cell clones. Characterization of specificity and function of CD4+ helper/cytotoxic and CD8+ cytotoxic T cell clones.

RS Van Binnendijk, MC Poelen, P De Vries… - … (Baltimore, Md.: 1950 …, 1989 - journals.aai.org
PBMC from healthy adult individuals seropositive for measles virus (MV) were tested for
their capacity to proliferate to UV-inactivated MV (UV-MV) or to autologous MV-infected EBV-…

[HTML][HTML] Inactivation of eIF2B and phosphorylation of PHAS-I in heat-shocked rat hepatoma cells

GC Scheper, J Mulder, M Kleijn, HO Voorma… - Journal of Biological …, 1997 - ASBMB
Various factors are involved in the heat shock-induced inhibition of protein synthesis. Changes
upon heat shock in phosphorylation, leading to inactivation, of eukaryotic initiation factors …

Purification and characterization of a protein factor that reverses the inhibition of protein synthesis by the heme‐regulated translational inhibitor in rabbit reticulocyte …

H Amesz, H Goumans… - European Journal of …, 1979 - Wiley Online Library
We have purified and partially characterized a supernatant factor which reverses the effect of
the heme‐regulated translational inhibitor on protein synthesis in rabbit reticulocyte lysates. …

Measles virus fusion protein presented in an immune-stimulating complex (iscom) induces haemolysis-inhibiting and fusion-inhibiting antibodies, virus-specific T cells …

P de Vries, RS Van Binnendijk… - Journal of general …, 1988 - microbiologyresearch.org
Immune-stimulating complexes (iscoms), which have recently been shown to be highly
effective for the antigenic presentation of membrane proteins of viruses, were prepared with …

Role of the 3′ untranslated region of baculovirus p10 mRNA in high-level expression of foreign genes

MM van Oers, JM Vlak, HO Voorma… - Journal of general …, 1999 - microbiologyresearch.org
The p10 gene of Autographa californica nucleopolyhedrovirus has two putative AATAAA
polyadenylation signals. The downstream signal is used predominantly, as was determined by …

Phosphorylation state of the cap-binding protein eIF4E during viral infection

M KLEIJN, CLJ VRINS, HO VOORMA, AAM THOMAS - Virology, 1996 - Elsevier
The eukaryotic translation initiation factor eIF4E, the cap-binding protein, seems to play an
essential role in the establishment of the host shut-off after viral infection. Infection with …