[HTML][HTML] Pro-and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells
M Li, BCAM Van Esch, GTM Wagenaar… - European journal of …, 2018 - Elsevier
In the gastro-intestinal tract, short chain fatty acids (SCFAs) have protective effects on
epithelial cells. However, their effects on inflammatory cytokine production by endothelial and …
epithelial cells. However, their effects on inflammatory cytokine production by endothelial and …
Two members of the Tcf family implicated in Wnt/β-catenin signaling during embryogenesis in the mouse
Tcf transcription factors interact with β-catenin and Armadillo to mediate Wnt/Wingless
signaling. We now report the characterization of genes encoding two murine members of the Tcf …
signaling. We now report the characterization of genes encoding two murine members of the Tcf …
Gene expression profile and histopathology of experimental bronchopulmonary dysplasia induced by prolonged oxidative stress
GTM Wagenaar, SAJ ter Horst, MA van Gastelen… - Free Radical Biology …, 2004 - Elsevier
Oxidative stress is an important factor in the pathogenesis of bronchopulmonary dysplasia (BPD),
a chronic lung disease of premature infants characterized by arrested alveolar and …
a chronic lung disease of premature infants characterized by arrested alveolar and …
Liver histopathology of the sharptooth catfish Clarias gariepinus as a biomarker of aquatic pollution
JC Van Dyk, MJ Cochrane, GM Wagenaar - Chemosphere, 2012 - Elsevier
This paper reports on a comparative perspective of liver histopathological data of the
sharptooth catfish Clarias gariepinus. The data was collected from a spectrum of relatively un-…
sharptooth catfish Clarias gariepinus. The data was collected from a spectrum of relatively un-…
Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension
S Umar, YP de Visser, P Steendijk… - American Journal …, 2009 - journals.physiology.org
Pulmonary arterial hypertension (PAH) is a chronic lung disease that leads to right ventricular
(RV) hypertrophy (RVH), remodeling, and failure. We tested treatment with bone marrow-…
(RV) hypertrophy (RVH), remodeling, and failure. We tested treatment with bone marrow-…
[HTML][HTML] Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury
YP De Visser, FJ Walther, EH Laghmani, H Boersma… - Respiratory …, 2009 - Springer
Background Phosphodiesterase-5 inhibition with sildenafil has been used to treat severe
pulmonary hypertension and bronchopulmonary dysplasia (BPD), a chronic lung disease in …
pulmonary hypertension and bronchopulmonary dysplasia (BPD), a chronic lung disease in …
Apelin attenuates hyperoxic lung and heart injury in neonatal rats
YP Visser, FJ Walther, EH Laghmani… - American journal of …, 2010 - atsjournals.org
Rationale: Apelin, a potent vasodilator and angiogenic factor, may be a novel therapeutic
agent in neonatal chronic lung disease, including bronchopulmonary dysplasia. Objectives: To …
agent in neonatal chronic lung disease, including bronchopulmonary dysplasia. Objectives: To …
Organochlorine pesticide levels in Clarias gariepinus from polluted freshwater impoundments in South Africa and associated human health risks
IEJ Barnhoorn, JC Van Dyk, B Genthe, WR Harding… - Chemosphere, 2015 - Elsevier
There are increasing concerns regarding the safe human consumption of fish from polluted,
freshwater impoundments. The aim of this study was to analyse the muscle tissue of the …
freshwater impoundments. The aim of this study was to analyse the muscle tissue of the …
Agonists of MAS oncogene and angiotensin II type 2 receptors attenuate cardiopulmonary disease in rats with neonatal hyperoxia-induced lung injury
GTM Wagenaar, EH Laghmani… - … of Physiology-Lung …, 2013 - journals.physiology.org
Stimulation of MAS oncogene receptor (MAS) or angiotensin (Ang) receptor type 2 (AT2) may
be novel therapeutic options for neonatal chronic lung disease (CLD) by counterbalancing …
be novel therapeutic options for neonatal chronic lung disease (CLD) by counterbalancing …
[HTML][HTML] Impaired healing of cutaneous wounds and colonic anastomoses in mice lacking thrombin-activatable fibrinolysis inhibitor
EA Te Velde, GTM Wagenaar, A Reijerkerk… - Journal of Thrombosis …, 2003 - Elsevier
Plasmin and other components of the plasminogen activation system play an important role
in tissue repair by regulating extracellular matrix remodeling, including fibrin degradation. …
in tissue repair by regulating extracellular matrix remodeling, including fibrin degradation. …
