Biological properties of extracellular vesicles and their physiological functions
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
A compendium of single extracellular vesicle flow cytometry
JA Welsh, GJA Arkesteijn, M Bremer… - Journal of …, 2023 - Wiley Online Library
Flow cytometry (FCM) offers a multiparametric technology capable of characterizing single
extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells, …
extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells, …
Concise review: developing best-practice models for the therapeutic use of extracellular vesicles
AT Reiner, KW Witwer, BWM Van Balkom… - Stem cells …, 2017 - academic.oup.com
Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as
therapeutic entities, particularly in stem cell-related approaches, has underlined the need for …
therapeutic entities, particularly in stem cell-related approaches, has underlined the need for …
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …
origin and change the functions and phenotypes of other cells. These features indicate …
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into
their microenvironment. Recent studies have elucidated the role of EVs in intercellular …
their microenvironment. Recent studies have elucidated the role of EVs in intercellular …
Obstacles and opportunities in the functional analysis of extracellular vesicle RNA–an ISEV position paper
The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has
been demonstrated in a multitude of different in vitro cell systems and in a variety of body fluids…
been demonstrated in a multitude of different in vitro cell systems and in a variety of body fluids…
Complete remission of experimental arthritis by joint targeting of glucocorticoids with long‐circulating liposomes
JM Metselaar, MHM Wauben… - … : Official Journal of …, 2003 - Wiley Online Library
Objective To increase the therapeutic activity of glucocorticoids in experimental arthritis by
encapsulation in long‐circulating polyethylene glycol liposomes, which have shown the ability …
encapsulation in long‐circulating polyethylene glycol liposomes, which have shown the ability …
Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions
ENM Nolte-'t Hoen, HPJ Buermans… - Nucleic acids …, 2012 - academic.oup.com
Cells release RNA-carrying vesicles and membrane-free RNA/protein complexes into the
extracellular milieu. Horizontal vesicle-mediated transfer of such shuttle RNA between cells …
extracellular milieu. Horizontal vesicle-mediated transfer of such shuttle RNA between cells …
MHC II in dendritic cells is targeted to lysosomes or T cell‐induced exosomes via distinct multivesicular body pathways
SI Buschow, ENM Nolte‐'t Hoen, G Van Niel, MS Pols… - Traffic, 2009 - Wiley Online Library
Dendritic cells (DCs) express major histocompatibility complex class II (MHC II) to present
peptide antigens to T cells. In immature DCs, which bear low cell surface levels of MHC II, …
peptide antigens to T cells. In immature DCs, which bear low cell surface levels of MHC II, …
Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry
EJ Van Der Vlist, ENM Nolte-'t Hoen, W Stoorvogel… - Nature protocols, 2012 - nature.com
We provide a protocol for a high-resolution flow cytometry–based method for quantitative and
qualitative analysis of individual nano-sized vesicles released by cells, as developed and …
qualitative analysis of individual nano-sized vesicles released by cells, as developed and …