Assessment of HPA-axis function in posttraumatic stress disorder: pharmacological and non-pharmacological challenge tests, a review

CS De Kloet, E Vermetten, E Geuze… - Journal of psychiatric …, 2006 - Elsevier
Posttraumatic stress disorder (PTSD) is typically accompanied by acute and chronic
alterations in the stress response. These alterations have mostly been described in individuals …

Glutamate and anxiety

V Bergink, HJGM Van Megen… - European …, 2004 - Elsevier
Although glutamate is a simple molecule, its actions in the limbic system and areas concerning
anxiety are complex and widespread. These actions are mediated through different …

Anxiety disorders: a review of tricyclic antidepressants and selective serotonin reuptake inhibitors

J Zohar, HGM Westenberg - Acta Psychiatrica Scandinavica, 2000 - Wiley Online Library
Zohar J, Westenberg HGM. Anxiety disorders: a review of tricyclic antidepressants and
selective serotonin reuptake inhibitors. Acta Psychiatr Scand 2000: 101: 39–49. © …

Genome-wide association study of obsessive-compulsive disorder

SE Stewart, D Yu, JM Scharf, BM Neale… - Molecular …, 2013 - nature.com
Obsessive-compulsive disorder (OCD) is a common, debilitating neuropsychiatric illness
with complex genetic etiology. The International OCD Foundation Genetics Collaborative (…

[HTML][HTML] The bovine protein α-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain …

CR Markus, B Olivier, GEM Panhuysen… - The American journal of …, 2000 - Elsevier
Background: Increased brain serotonin may improve the ability to cope with stress, whereas
a decline in serotonin activity is involved in depressive mood. The uptake of the serotonin …

[HTML][HTML] Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

LK Davis, D Yu, CL Keenan, ER Gamazon… - PLoS …, 2013 - journals.plos.org
The direct estimation of heritability from genome-wide common variant data as implemented
in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to …

Consensus statement on social anxiety disorder from the International Consensus Group on Depression and Anxiety

JC Ballenger, JRT Davidson, Y Lecrubier… - Journal of Clinical …, 1998 - psychiatrist.com
Objective: The goal of this consensus statement is to provide primary care clinicians with a
better understanding of management issues in social anxiety disorder (social phobia) and …

A double-blind, randomized, placebo-controlled trial of quetiapine addition in patients with obsessive-compulsive disorder refractory to serotonin reuptake inhibitors

D Denys, F de Geus, H Van Megen… - Journal of Clinical …, 2004 - psychiatrist.com
Background: Although serotonin reuptake inhibitors (SRIs) are the most effective pharmacologic
treatment currently available for patients with obsessive-compulsive disorder (OCD), 40…

Low level of dopaminergic D2 receptor binding in obsessive-compulsive disorder

D Denys, N van der Wee, J Janssen, F De Geus… - Biological …, 2004 - Elsevier
BACKGROUND: Despite growing evidence for involvement of the dopaminergic system in
obsessive-compulsive disorder (OCD), the functional anatomy of the dopaminergic system in …

Altered pain processing in veterans with posttraumatic stress disorder

E Geuze, HGM Westenberg, A Jochims… - Archives of general …, 2007 - jamanetwork.com
Context Posttraumatic stress disorder (PTSD) is a chronic and debilitating anxiety disorder.
Several brain areas related to pain processing are implicated in PTSD. To our knowledge, no …