Gebruikersprofielen voor "Westra, H. "
 | Harm-Jan WestraPostdoc at the University Medical Center Groningen Geverifieerd e-mailadres voor umcg.nl Geciteerd door 37451 |
Gaps in accessing treatment for anxiety and depression: challenges for the delivery of care
KA Collins, HA Westra, DJA Dozois, DD Burns - Clinical psychology review, 2004 - Elsevier
Epidemiological studies have identified high prevalence rates of anxiety and depression in
North America [eg, J. of Nerv. Ment. Dis. 182 (1994) 290]. However, only a small percentage …
North America [eg, J. of Nerv. Ment. Dis. 182 (1994) 290]. However, only a small percentage …
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption
Coffee, a major dietary source of caffeine, is among the most widely consumed beverages in
the world and has received considerable attention regarding health risks and benefits. We …
the world and has received considerable attention regarding health risks and benefits. We …
[HTML][HTML] From genome to function by studying eQTLs
Genome-wide association studies (GWASs) have shown a large number of genetic variants
to be associated with complex diseases. The identification of the causal variant within an …
to be associated with complex diseases. The identification of the causal variant within an …
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
Trait-associated genetic variants affect complex phenotypes primarily via regulatory mechanisms
on the transcriptome. To investigate the genetics of gene expression, we performed cis…
on the transcriptome. To investigate the genetics of gene expression, we performed cis…
Large-scale association analyses identify host factors influencing human gut microbiome composition
A Kurilshikov, C Medina-Gomez, R Bacigalupe… - Nature …, 2021 - nature.com
To study the effect of host genetics on gut microbiome composition, the MiBioGen consortium
curated and analyzed genome-wide genotypes and 16S fecal microbiome data from …
curated and analyzed genome-wide genotypes and 16S fecal microbiome data from …
Genetics of rheumatoid arthritis contributes to biology and drug discovery
A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated
variants with diverse genomic and biological data sets to provide insight into …
variants with diverse genomic and biological data sets to provide insight into …
Defining the role of common variation in the genomic and biological architecture of adult human height
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide
significance that together explained one-fifth of the heritability for adult height. By testing …
significance that together explained one-fifth of the heritability for adult height. By testing …
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…
Systematic identification of trans eQTLs as putative drivers of known disease associations
Identifying the downstream effects of disease-associated SNPs is challenging. To help
overcome this problem, we performed expression quantitative trait locus (eQTL) meta-analysis in …
overcome this problem, we performed expression quantitative trait locus (eQTL) meta-analysis in …
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Ulcerative colitis and Crohn's disease are the two main forms of inflammatory bowel disease
(IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or …
(IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or …