Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel

U Creutzig, MM van Den Heuvel-Eibrink… - Blood, The Journal …, 2012 - ashpublications.org
Despite major improvements in outcome over the past decades, acute myeloid leukemia (AML)
remains a life-threatening malignancy in children, with current survival rates of ∼ 70%. …

[HTML][HTML] Collaborative efforts driving progress in pediatric acute myeloid leukemia

CM Zwaan, EA Kolb, D Reinhardt… - Journal of clinical …, 2015 - ncbi.nlm.nih.gov
Diagnosis, treatment, response monitoring, and outcome of pediatric acute myeloid leukemia
(AML) have made enormous progress during the past decades. Because AML is a rare …

Elements and patterns in the solar magnetic field

C Zwaan - Annual review of astronomy and astrophysics, 1987 - annualreviews.org
The intricate time-dependent structure and the non thermal processes in the solar atmosphere
indicate the importance of magnetic fields in turbulent cosmical bodies. We are now …

[HTML][HTML] The MLL recombinome of acute leukemias in 2017

C Meyer, T Burmeister, D Gröger, G Tsaur, L Fechina… - Leukemia, 2018 - nature.com
Chromosomal rearrangements of the human MLL/KMT2A gene are associated with infant,
pediatric, adult and therapy-induced acute leukemias. Here we present the data obtained …

[HTML][HTML] Results from an extensive Einstein stellar survey

GS Vaiana, JP Cassinelli, G Fabbiano… - … Journal, Part 1, vol …, 1981 - adsabs.harvard.edu
The preliminary results of the Einstein Observatory stellar X-ray survey are presented. To
date, 143 soft X-ray sources have been identified with stellar counterparts, leaving no doubt …

[HTML][HTML] The MLL recombinome of acute leukemias in 2013

C Meyer, J Hofmann, T Burmeister, D Gröger, TS Park… - Leukemia, 2013 - nature.com
Chromosomal rearrangements of the human MLL (mixed lineage leukemia) gene are
associated with high-risk infant, pediatric, adult and therapy-induced acute leukemias. We used …

Magnetic braking in low-mass X-ray binaries.

F Verbunt, C Zwaan - Astronomy and Astrophysics, 1981 - ui.adsabs.harvard.edu
It is pointed out that the cool main-sequence components of cataclysmic binaries and low-mass
X-ray binaries will undergo rotational braking by a magnetically coupled stellar wind, in a …

Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study

BV Balgobind, SC Raimondi, J Harbott… - Blood, The Journal …, 2009 - ashpublications.org
Translocations involving chromosome 11q23 frequently occur in pediatric acute myeloid
leukemia (AML) and are associated with poor prognosis. In most cases, the MLL gene is …

Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome–positive leukemia

K Porkka, P Koskenvesa, T Lundán… - Blood, The Journal …, 2008 - ashpublications.org
Although imatinib, a BCR-ABL tyrosine kinase inhibitor, is used to treat acute Philadelphia
chromosome–positive (Ph + ) leukemia, it does not prevent central nervous system (CNS) …

Phase I/phase II study of blinatumomab in pediatric patients with relapsed/refractory acute lymphoblastic leukemia

A von Stackelberg, F Locatelli, G Zugmaier… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Blinatumomab is a bispecific T-cell engager antibody construct targeting CD19 on
B-cell lymphoblasts. We evaluated the safety, pharmacokinetics, recommended dosage, and …