| An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus D Lamarre, PC Anderson, M Bailey, P Beaulieu, G Bolger, P Bonneau, ... Nature 426 (6963), 186-189, 2003 | 1142 | 2003 |
| Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors L Doyon, G Croteau, D Thibeault, F Poulin, L Pilote, D Lamarre Journal of virology 70 (6), 3763-3769, 1996 | 392 | 1996 |
| Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors G Croteau, L Doyon, D Thibeault, G McKercher, L Pilote, D Lamarre Journal of Virology 71 (2), 1089-1096, 1997 | 315 | 1997 |
| Peptide-based inhibitors of the hepatitis C virus serine protease M Llinas-Brunet, M Bailey, G Fazal, S Goulet, T Halmos, S Laplante, ... Bioorganic & Medicinal Chemistry Letters 8 (13), 1713-1718, 1998 | 284 | 1998 |
| Macrocyclic inhibitors of the NS3 protease as potential therapeutic agents of hepatitis C virus infection YS Tsantrizos, G Bolger, P Bonneau, DR Cameron, N Goudreau, G Kukolj, ... Angewandte Chemie 115 (12), 1394-1398, 2003 | 260 | 2003 |
| Structure− activity study on a novel series of macrocyclic inhibitors of the hepatitis C virus NS3 protease leading to the discovery of BILN 2061 M Llinas-Brunet, MD Bailey, G Bolger, C Brochu, AM Faucher, JM Ferland, ... Journal of Medicinal Chemistry 47 (7), 1605-1608, 2004 | 234 | 2004 |
| MAVS dimer is a crucial signaling component of innate immunity and the target of hepatitis C virus NS3/4A protease M Baril, ME Racine, F Penin, D Lamarre Journal of virology 83 (3), 1299-1311, 2009 | 213 | 2009 |
| Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding site S Fleury, D Lamarre, S Meloche, SE Ryu, C Cantin, WA Hendrickson, ... Cell 66 (5), 1037-1049, 1991 | 206 | 1991 |
| The MHC-binding and gp120-binding functions of CD4 are separable D Lamarre, A Ashkenazi, S Fleury, DH Smith, RP Sekaly, DJ Capon Science 245 (4919), 743-746, 1989 | 189 | 1989 |
| Interleukin‐10‐induced MARCH1 mediates intracellular sequestration of MHC class II in monocytes J Thibodeau, MC Bourgeois‐Daigneault, G Huppé, J Tremblay, A Aumont, ... European journal of immunology 38 (5), 1225-1230, 2008 | 185 | 2008 |
| Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease: towards smaller inhibitors M Llinàs-Brunet, M Bailey, G Fazal, E Ghiro, V Gorys, S Goulet, T Halmos, ... Bioorganic & medicinal chemistry letters 10 (20), 2267-2270, 2000 | 163 | 2000 |
| Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine protease M Llinàs-Brunet, M Bailey, R Déziel, G Fazal, V Gorys, S Goulet, T Halmos, ... Bioorganic & Medicinal Chemistry Letters 8 (19), 2719-2724, 1998 | 146 | 1998 |
| Requirement of NOX2 and reactive oxygen species for efficient RIG-I-mediated antiviral response through regulation of MAVS expression A Soucy-Faulkner, E Mukawera, K Fink, A Martel, L Jouan, Y Nzengue, ... PLoS pathogens 6 (6), e1000930, 2010 | 144 | 2010 |
| An NS3 serine protease inhibitor abrogates replication of subgenomic hepatitis C virus RNA A Pause, G Kukolj, M Bailey, M Brault, F Dô, T Halmos, L Lagacé, ... Journal of Biological Chemistry 278 (22), 20374-20380, 2003 | 122 | 2003 |
| Specific inhibitors of HCV polymerase identified using an NS5B with lower affinity for template/primer substrate G McKercher, PL Beaulieu, D Lamarre, S LaPlante, S Lefebvre, C Pellerin, ... Nucleic acids research 32 (2), 422-431, 2004 | 112 | 2004 |
| Peptide-Based Inhibitors of the Hepatitis C Virus NS3 Protease: Structure−Activity Relationship at the C-Terminal Position J Rancourt, DR Cameron, V Gorys, D Lamarre, M Poirier, D Thibeault, ... Journal of medicinal chemistry 47 (10), 2511-2522, 2004 | 108 | 2004 |
| Sensitivity of NS3 serine proteases from hepatitis C virus genotypes 2 and 3 to the inhibitor BILN 2061 D Thibeault, C Bousquet, R Gingras, L Lagacé, R Maurice, PW White, ... Journal of virology 78 (14), 7352-7359, 2004 | 105 | 2004 |
| Solution structure of substrate-based ligands when bound to hepatitis C virus NS3 protease domain SR LaPlante, DR Cameron, N Aubry, S Lefebvre, G Kukolj, R Maurice, ... Journal of Biological Chemistry 274 (26), 18618-18624, 1999 | 104 | 1999 |
| Hepatitis C virus subgenomic replicons in the human embryonic kidney 293 cell line S Ali, C Pellerin, D Lamarre, G Kukolj Journal of virology 78 (1), 491-501, 2004 | 101 | 2004 |
| Class II MHC molecules and the HIV gp 120 envelope protein interact with functionally distinct regions of the CD4 molecule. D Lamarre, DJ Capon, DR Karp, T Gregory, EO Long, RP Sekaly The EMBO Journal 8 (11), 3271-3277, 1989 | 97 | 1989 |
