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Martijn Verdoes
Martijn Verdoes
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Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib
CR Berkers, M Verdoes, E Lichtman, E Fiebiger, BM Kessler, ...
Nature methods 2 (5), 357-362, 2005
3162005
Molecular repolarisation of tumour-associated macrophages
FJ Van Dalen, MHME Van Stevendaal, FL Fennemann, M Verdoes, ...
Molecules 24 (1), 9, 2018
2542018
A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo
M Verdoes, BI Florea, V Menendez-Benito, CJ Maynard, MD Witte, ...
Chemistry & biology 13 (11), 1217-1226, 2006
2282006
Improved quenched fluorescent probe for imaging of cysteine cathepsin activity
M Verdoes, K Oresic Bender, E Segal, WA van der Linden, S Syed, ...
Journal of the American Chemical Society 135 (39), 14726-14730, 2013
2052013
Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics
KH Richau, F Kaschani, M Verdoes, TC Pansuriya, S Niessen, K Stüber, ...
Plant physiology 158 (4), 1583-1599, 2012
2012012
New approaches for dissecting protease functions to improve probe development and drug discovery
E Deu, M Verdoes, M Bogyo
Nature structural & molecular biology 19 (1), 9-16, 2012
1922012
Selective inhibitor of proteasome's caspase-like sites sensitizes cells to specific inhibition of chymotrypsin-like sites
M Britton, MM Lucas, SL Downey, M Screen, AA Pletnev, M Verdoes, ...
Chemistry & biology 16 (12), 1278-1289, 2009
1912009
Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes
LE Edgington, M Verdoes, M Bogyo
Current opinion in chemical biology 15 (6), 798-805, 2011
1882011
Glutaminyl cyclase is an enzymatic modifier of the CD47-SIRPα axis and a target for cancer immunotherapy
MEW Logtenberg, JHM Jansen, M Raaben, M Toebes, K Franke, ...
Nature medicine 25 (4), 612-619, 2019
1672019
Functional imaging of legumain in cancer using a new quenched activity-based probe
LE Edgington, M Verdoes, A Ortega, NP Withana, J Lee, S Syed, ...
Journal of the American Chemical Society 135 (1), 174-182, 2013
1632013
Characterization of the ubiquitin–proteasome system in bortezomib-adapted cells
T Rückrich, M Kraus, J Gogel, A Beck, H Ovaa, M Verdoes, HS Overkleeft, ...
Leukemia 23 (6), 1098-1105, 2009
1632009
Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib
AC Mirabella, AA Pletnev, SL Downey, BI Florea, TB Shabaneh, M Britton, ...
Chemistry & biology 18 (5), 608-618, 2011
1292011
An unusual reverse turn structure adopted by a furanoid sugar amino acid incorporated in gramicidin S
GM Grotenbreg, MSM Timmer, AL Llamas-Saiz, M Verdoes, ...
Journal of the American Chemical Society 126 (11), 3444-3446, 2004
1222004
A nonpeptidic cathepsin S activity-based probe for noninvasive optical imaging of tumor-associated macrophages
M Verdoes, LE Edgington, FA Scheeren, M Leyva, G Blum, K Weiskopf, ...
Chemistry & biology 19 (5), 619-628, 2012
1172012
Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit β5t
BI Florea, M Verdoes, N Li, WA van der Linden, PP Geurink, ...
Chemistry & biology 17 (8), 795-801, 2010
1172010
Design of protease activated optical contrast agents that exploit a latent lysosomotropic effect for use in fluorescence-guided surgery
LO Ofori, NP Withana, TR Prestwood, M Verdoes, JJ Brady, MM Winslow, ...
ACS chemical biology 10 (9), 1977-1988, 2015
1122015
Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS
N Li, CL Kuo, G Paniagua, H Van Den Elst, M Verdoes, LI Willems, ...
Nature protocols 8 (6), 1155-1168, 2013
1032013
Non-invasive imaging of idiopathic pulmonary fibrosis using cathepsin protease probes
NP Withana, X Ma, HM McGuire, M Verdoes, WA van der Linden, LO Ofori, ...
Scientific reports 6 (1), 19755, 2016
992016
Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity
H Li, EL Ponder, M Verdoes, KH Asbjornsdottir, E Deu, LE Edgington, ...
Chemistry & biology 19 (12), 1535-1545, 2012
942012
A Rab20-dependent membrane trafficking pathway controls M. tuberculosis replication by regulating phagosome spaciousness and integrity
L Schnettger, A Rodgers, U Repnik, RP Lai, G Pei, M Verdoes, ...
Cell host & microbe 21 (5), 619-628. e5, 2017
902017
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Artikelen 1–20