Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib CR Berkers, M Verdoes, E Lichtman, E Fiebiger, BM Kessler, ... Nature methods 2 (5), 357-362, 2005 | 316 | 2005 |
Molecular repolarisation of tumour-associated macrophages FJ Van Dalen, MHME Van Stevendaal, FL Fennemann, M Verdoes, ... Molecules 24 (1), 9, 2018 | 254 | 2018 |
A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo M Verdoes, BI Florea, V Menendez-Benito, CJ Maynard, MD Witte, ... Chemistry & biology 13 (11), 1217-1226, 2006 | 228 | 2006 |
Improved quenched fluorescent probe for imaging of cysteine cathepsin activity M Verdoes, K Oresic Bender, E Segal, WA van der Linden, S Syed, ... Journal of the American Chemical Society 135 (39), 14726-14730, 2013 | 205 | 2013 |
Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics KH Richau, F Kaschani, M Verdoes, TC Pansuriya, S Niessen, K Stüber, ... Plant physiology 158 (4), 1583-1599, 2012 | 201 | 2012 |
New approaches for dissecting protease functions to improve probe development and drug discovery E Deu, M Verdoes, M Bogyo Nature structural & molecular biology 19 (1), 9-16, 2012 | 192 | 2012 |
Selective inhibitor of proteasome's caspase-like sites sensitizes cells to specific inhibition of chymotrypsin-like sites M Britton, MM Lucas, SL Downey, M Screen, AA Pletnev, M Verdoes, ... Chemistry & biology 16 (12), 1278-1289, 2009 | 191 | 2009 |
Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes LE Edgington, M Verdoes, M Bogyo Current opinion in chemical biology 15 (6), 798-805, 2011 | 188 | 2011 |
Glutaminyl cyclase is an enzymatic modifier of the CD47-SIRPα axis and a target for cancer immunotherapy MEW Logtenberg, JHM Jansen, M Raaben, M Toebes, K Franke, ... Nature medicine 25 (4), 612-619, 2019 | 167 | 2019 |
Functional imaging of legumain in cancer using a new quenched activity-based probe LE Edgington, M Verdoes, A Ortega, NP Withana, J Lee, S Syed, ... Journal of the American Chemical Society 135 (1), 174-182, 2013 | 163 | 2013 |
Characterization of the ubiquitin–proteasome system in bortezomib-adapted cells T Rückrich, M Kraus, J Gogel, A Beck, H Ovaa, M Verdoes, HS Overkleeft, ... Leukemia 23 (6), 1098-1105, 2009 | 163 | 2009 |
Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib AC Mirabella, AA Pletnev, SL Downey, BI Florea, TB Shabaneh, M Britton, ... Chemistry & biology 18 (5), 608-618, 2011 | 129 | 2011 |
An unusual reverse turn structure adopted by a furanoid sugar amino acid incorporated in gramicidin S GM Grotenbreg, MSM Timmer, AL Llamas-Saiz, M Verdoes, ... Journal of the American Chemical Society 126 (11), 3444-3446, 2004 | 122 | 2004 |
A nonpeptidic cathepsin S activity-based probe for noninvasive optical imaging of tumor-associated macrophages M Verdoes, LE Edgington, FA Scheeren, M Leyva, G Blum, K Weiskopf, ... Chemistry & biology 19 (5), 619-628, 2012 | 117 | 2012 |
Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit β5t BI Florea, M Verdoes, N Li, WA van der Linden, PP Geurink, ... Chemistry & biology 17 (8), 795-801, 2010 | 117 | 2010 |
Design of protease activated optical contrast agents that exploit a latent lysosomotropic effect for use in fluorescence-guided surgery LO Ofori, NP Withana, TR Prestwood, M Verdoes, JJ Brady, MM Winslow, ... ACS chemical biology 10 (9), 1977-1988, 2015 | 112 | 2015 |
Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS N Li, CL Kuo, G Paniagua, H Van Den Elst, M Verdoes, LI Willems, ... Nature protocols 8 (6), 1155-1168, 2013 | 103 | 2013 |
Non-invasive imaging of idiopathic pulmonary fibrosis using cathepsin protease probes NP Withana, X Ma, HM McGuire, M Verdoes, WA van der Linden, LO Ofori, ... Scientific reports 6 (1), 19755, 2016 | 99 | 2016 |
Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity H Li, EL Ponder, M Verdoes, KH Asbjornsdottir, E Deu, LE Edgington, ... Chemistry & biology 19 (12), 1535-1545, 2012 | 94 | 2012 |
A Rab20-dependent membrane trafficking pathway controls M. tuberculosis replication by regulating phagosome spaciousness and integrity L Schnettger, A Rodgers, U Repnik, RP Lai, G Pei, M Verdoes, ... Cell host & microbe 21 (5), 619-628. e5, 2017 | 90 | 2017 |